5-Fluoro-2-nitrobenzaldehyde
- CAS No.395-81-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Fluoro-2-nitrobenzaldehyde (CAS 395-81-3) designed for advanced organic synthesis applications. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
5-Fluoro-2-nitrobenzaldehyde is a highly specialized fluorinated aromatic intermediate essential for modern pharmaceutical and agrochemical synthesis. As a key building block, this compound features a unique structural arrangement where a fluorine atom and a nitro group are positioned on the benzaldehyde backbone. This specific substitution pattern enhances the reactivity of the molecule, making it an invaluable precursor for constructing complex heterocyclic systems and biologically active compounds. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial production scales.
The introduction of fluorine into organic molecules is a critical strategy in medicinal chemistry to improve metabolic stability and bioavailability. Consequently, 5-Fluoro-2-nitrobenzaldehyde serves as a vital starting material for developing next-generation therapeutics. We maintain strict control over every production batch to guarantee that the chemical properties align with international standards, providing our partners with a reliable supply chain for their synthesis projects.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Fluoro-2-nitrobenzaldehyde |
| CAS Number | 395-81-3 |
| Molecular Formula | C7H4FNO3 |
| Molecular Weight | 169.11 g/mol |
| Appearance | Pale yellow crystalline powder |
| Purity | ≥99.0% |
| Melting Point | 92-94°C |
| Boiling Point | 153°C |
| Density | 1.443 g/cm³ |
| Refractive Index | 1.524 |
Industrial Applications
This fluorinated aldehyde is primarily utilized as an intermediate in the synthesis of pharmaceuticals, particularly in the creation of kinase inhibitors and other targeted therapies. The nitro group allows for further reduction to amines, facilitating the formation of diverse chemical libraries. Additionally, it finds application in the agrochemical sector for producing herbicides and fungicides where fluorinated structures offer enhanced environmental stability and efficacy.
Organic chemists value this compound for its versatility in cross-coupling reactions and nucleophilic substitutions. The presence of the fluorine atom often influences the electronic properties of the final product, optimizing binding affinity to biological targets. Whether used in laboratory-scale research or large-scale manufacturing, 5-Fluoro-2-nitrobenzaldehyde provides a robust foundation for complex molecular architecture.
Quality Assurance and Storage
- Each batch undergoes rigorous analysis using HPLC and NMR to confirm identity and purity.
- Certificate of Analysis (COA) is provided with every shipment to ensure traceability.
- Packaged in 25 kg drums or customized according to specific client requirements.
- Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight.
- Proper sealing is required to prevent moisture absorption and maintain stability over time.
Our commitment to quality extends beyond the product itself. We offer comprehensive technical support to assist with integration into your specific synthesis routes. By choosing our facility as your global manufacturer, you gain access to industrial purity standards and competitive bulk pricing. Contact our sales team today to discuss your volume requirements and receive detailed technical data sheets.
