Intermediates

5-Fluoro-2-nitrotoluene

  • CAS No.446-33-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Fluoro-2-nitrotoluene (CAS 446-33-3) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate manufacturing.

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Product Technical Details

Product Overview

5-Fluoro-2-nitrotoluene is a critical fluorinated aromatic compound widely utilized in the field of advanced organic synthesis. As a key building block, this chemical serves as an essential precursor for the development of various pharmaceutical agents and agrochemical products. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research laboratories and industrial production facilities alike. The presence of both fluoro and nitro functional groups on the toluene backbone provides unique reactivity profiles, enabling chemists to perform selective substitutions and transformations efficiently.

We understand the importance of reliability in the supply chain for fine chemicals. Therefore, every batch of 5-Fluoro-2-nitrotoluene undergoes rigorous quality control testing to meet international standards. This commitment to excellence ensures that downstream synthesis processes proceed smoothly without unexpected impurities affecting yield or safety. Whether used in the creation of novel drug candidates or specialized agricultural formulations, this intermediate provides a solid foundation for chemical innovation.

Technical Specifications

The following table outlines the key physical and chemical properties of our premium grade 5-Fluoro-2-nitrotoluene. These parameters are verified through advanced analytical techniques to guarantee compliance with specified standards.

ParameterValue
CAS Number446-33-3
Molecular FormulaC7H6FNO2
Molecular Weight155.126 g/mol
AppearanceLight yellow liquid
Assay (Purity)≥98.0%
Density1.3±0.1 g/cm3
Boiling Point227.5±0.0 °C at 760 mmHg
Melting Point28°C
Flash Point87.8±0.0 °C
Refractive Index1.530

Industrial Applications

This fluorinated intermediate is primarily employed in the synthesis of complex organic molecules. Its specific substitution pattern allows for targeted chemical modifications, which is crucial in medicinal chemistry where structure-activity relationships are carefully optimized. Common applications include the production of pharmaceutical intermediates requiring fluorine incorporation to enhance metabolic stability or bioavailability. Additionally, it finds use in the agrochemical sector for developing pesticides and herbicides with improved environmental profiles.

  • Pharmaceutical intermediate synthesis
  • Agrochemical formulation development
  • Fluorinated polymer research
  • Custom organic synthesis projects

Quality Assurance and Storage

Safety and stability are paramount when handling chemical intermediates. Our 5-Fluoro-2-nitrotoluene is packaged in secure drums suitable for bulk transport, typically 200 kg per drum, though custom packaging solutions are available to meet specific logistical requirements. To maintain product integrity, storage should be in a cool, ventilated area away from direct sunlight and incompatible materials. We provide a Certificate of Analysis (COA) with every shipment, documenting the test results and ensuring full traceability. Our global manufacturing network supports timely delivery, helping you maintain efficient production schedules without compromise.