5-Fluoro-2-oxindole
- CAS No.56341-41-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Fluoro-2-oxindole (CAS 56341-41-4) designed for pharmaceutical API synthesis. Reliable supply for kinase inhibitor intermediate manufacturing with strict quality control.
Request Bulk PricingProduct Technical Details
Product Overview
5-Fluoro-2-oxindole is a specialized fluorinated heterocyclic compound that serves as a vital building block in modern medicinal chemistry. As a key structural motif, this oxindole derivative is extensively utilized in the development of advanced pharmaceutical agents, particularly within the oncology therapeutic sector. The introduction of a fluorine atom at the fifth position of the indole ring significantly enhances the metabolic stability and binding affinity of downstream drug candidates, making this intermediate highly valuable for complex organic synthesis.
Our manufacturing facility produces this compound under stringent quality management systems to ensure consistency across batches. We understand that the purity of starting materials directly impacts the yield and safety of the final active pharmaceutical ingredient. Therefore, every production run undergoes rigorous analytical testing to confirm compliance with international pharmaceutical standards.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Fluoro-2-oxindole |
| CAS Registry Number | 56341-41-4 |
| Molecular Formula | C8H6FNO |
| Molecular Weight | 151.14 g/mol |
| Appearance | Light brown powder |
| Purity (HPLC) | ≥98.0% |
| Melting Point | 143-147°C |
| Moisture Content | ≤0.5% |
| Residue on Ignition | ≤0.5% |
Industrial Applications
This chemical intermediate is primarily employed in the synthesis of kinase inhibitors, which are critical components in targeted cancer therapies. Specifically, it acts as a precursor in the manufacturing pathway of multi-targeted receptor tyrosine kinase inhibitors. The high reactivity of the oxindole core allows for versatile functionalization, enabling chemists to construct complex molecular architectures required for next-generation therapeutics.
Beyond oncology, fluorinated oxindoles are increasingly explored in neurological and anti-inflammatory research due to their favorable pharmacokinetic profiles. Our clients utilize this material for process development, scale-up activities, and commercial API production. We support both research-scale quantities and large-scale industrial demands.
Quality Assurance and Logistics
Quality is the cornerstone of our operation. Each batch of 5-Fluoro-2-oxindole is accompanied by a comprehensive Certificate of Analysis (COA) detailing all critical quality attributes. We employ high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify structural integrity and purity levels. Moisture control is strictly maintained to prevent degradation during storage and transport.
- Packaged in 25 kg drums or customized containers based on client requirements.
- Stored in a cool, ventilated environment to maintain stability.
- Global shipping capabilities with compliant hazardous material documentation.
- Technical support available for synthesis route optimization.
We are committed to providing reliable supply chains for the global pharmaceutical industry. Contact our sales team for detailed pricing, lead times, and sample availability. Please note that products under valid patents are not offered to countries covered by such patents, ensuring full regulatory compliance in all transactions.
