5-Fluoro-3-nitropyridin-2-amine
- CAS No.212268-12-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Fluoro-3-nitropyridin-2-amine (CAS 212268-12-7), a key fluorinated heterocyclic intermediate for advanced pharmaceutical synthesis.
Request Bulk PricingProduct Technical Details
Product Overview
5-Fluoro-3-nitropyridin-2-amine is a high-value fluorinated heterocyclic compound widely employed as a critical building block in the development of complex pharmaceutical active ingredients. With its unique combination of electron-withdrawing nitro and fluoro substituents on the pyridine core, this molecule offers exceptional reactivity and selectivity in multi-step synthetic sequences, particularly in cross-coupling and nucleophilic aromatic substitution reactions.
Specifications
| Molecular Formula | C5H4FN3O2 |
|---|---|
| Molecular Weight | 157.10 g/mol |
| CAS Number | 212268-12-7 |
| Appearance | White Crystalline Powder |
| Purity | ≥99.0% |
| Density | 1.6 ± 0.1 g/cm³ |
| Boiling Point | 290.1 ± 35.0 °C at 760 mmHg |
| Flash Point | 129.3 ± 25.9 °C |
| Refractive Index | 1.612 |
Industrial Applications
This compound serves primarily as a specialized intermediate in the synthesis of advanced organic molecules targeting neurological therapeutics and other regulated pharmaceutical pathways. Its structural features enable precise functionalization, making it indispensable in modern medicinal chemistry campaigns.
- Ideal for constructing fluorinated pyridine-based pharmacophores
- Compatible with Pd-catalyzed coupling methodologies
- Enables rapid diversification via selective reduction or displacement
Stored in tightly sealed containers under cool, dry conditions to maintain stability and prevent moisture uptake. Supplied in 5 kg drums for industrial-scale procurement.
