5-Fluoroindole
- CAS No.399-52-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Fluoroindole (CAS 399-52-0) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical intermediates.
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Product Overview
5-Fluoroindole is a critically important heterocyclic compound widely utilized in the field of medicinal chemistry and advanced organic synthesis. Characterized by the substitution of a fluorine atom at the fifth position of the indole ring, this chemical building block offers unique reactivity and metabolic stability profiles essential for modern drug discovery. Our facility produces this compound under strict quality management systems to ensure consistency and reliability for research and industrial applications. As a key intermediate, it serves as a foundational structure for developing various pharmaceutical agents, agrochemicals, and functional materials.
The introduction of fluorine into organic molecules often enhances biological activity, lipophilicity, and metabolic resistance. Therefore, securing a high-quality source of 5-Fluoroindole is vital for chemists aiming to optimize lead compounds. We specialize in providing this material with superior purity levels, ensuring that downstream reactions proceed with minimal impurities and maximum yield.
Technical Specifications
Quality is the cornerstone of our manufacturing process. Each batch of 5-Fluoroindole undergoes rigorous analytical testing to verify compliance with established specifications. The following table outlines the key physical and chemical properties associated with our standard grade product:
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Fluoroindole |
| CAS Number | 399-52-0 |
| Molecular Formula | C8H6FN |
| Molecular Weight | 135.138 g/mol |
| Appearance | Off-white powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 45-48 °C |
| Boiling Point | 258.0±13.0 °C |
| Density | 1.3±0.1 g/cm3 |
| Storage Condition | 2-8°C |
These specifications are verified using advanced instrumentation including High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. We maintain detailed records for every production lot to ensure full traceability.
Industrial Applications
The primary application of 5-Fluoroindole lies in the synthesis of complex pharmaceutical intermediates. It is frequently employed in the development of kinase inhibitors, receptor modulators, and other therapeutic agents where the indole scaffold is privileged. The fluorine substituent allows medicinal chemists to fine-tune the electronic properties of the molecule without significantly altering its steric profile.
Beyond pharmaceuticals, this compound finds utility in the agrochemical sector for creating novel pesticides and herbicides. Additionally, it is used in material science for the development of organic light-emitting diodes (OLEDs) and other electronic materials where specific electronic characteristics are required. Our manufacturing process is designed to support both small-scale research needs and large-scale commercial production.
Quality Assurance and Safety
We adhere to international safety and quality standards. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for that specific batch. Our packaging ensures the product remains stable during transit, typically utilizing 25 kg drums or custom configurations based on client requirements. Proper storage in a cool, ventilated place at 2-8°C is recommended to maintain integrity over time.
Safety data sheets (SDS) are provided to ensure safe handling within your laboratory or facility. We are committed to being a reliable global partner, offering competitive bulk pricing and consistent supply chains to support your production schedules without interruption.
