Intermediates

5-Fluoroisatin

  • CAS No.443-69-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Fluoroisatin (CAS 443-69-6) designed for advanced organic synthesis and pharmaceutical intermediate applications with global supply.

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Product Technical Details

Product Overview

5-Fluoroisatin represents a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis and medicinal chemistry. As a strategic derivative of the isatin core, this molecule incorporates a fluorine atom at the fifth position, significantly enhancing its reactivity profile and biological potential compared to non-fluorinated analogs. Our facility produces this compound under stringent quality control standards to ensure consistent performance in complex downstream applications. The introduction of fluorine into organic scaffolds is a widely recognized approach in pharmaceutical development to improve metabolic stability, bioavailability, and binding affinity.

We understand the demanding requirements of pharmaceutical research laboratories and industrial production facilities. Therefore, our 5-Fluoroisatin is synthesized using advanced catalytic methods that maximize yield while minimizing trace impurities. This commitment to excellence makes it an ideal choice for researchers and procurement managers seeking reliable raw materials for intricate synthetic routes. We prioritize batch-to-batch consistency to support your long-term development projects.

Technical Specifications

The following table outlines the key physical and chemical properties of our premium grade 5-Fluoroisatin. Each production batch is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with these strict specifications. Our quality assurance team utilizes state-of-the-art analytical instrumentation to validate every parameter.

CAS Number443-69-6
Molecular FormulaC8H4FNO2
Molecular Weight165.12 g/mol
AppearanceRed crystalline powder
Assay≥98.0%
Loss on Drying≤0.7%
Melting Point224-227°C
Boiling Point417.9°C
Density1.446 g/cm3

Industrial Applications

This fluorinated intermediate is extensively utilized in the development of pharmaceutical agents, particularly in the synthesis of kinase inhibitors and other therapeutic candidates targeting various disease pathways. The electron-withdrawing nature of the fluorine substituent allows for unique chemical transformations that are essential in constructing complex molecular architectures. Beyond pharmaceuticals, it finds valuable application in agrochemical research and material science where specific electronic properties are required for performance enhancement.

  • Pharmaceutical intermediate for drug discovery programs
  • Synthetic building block for novel heterocyclic compounds
  • Research reagent for advanced organic chemistry studies
  • Precursor for fluorinated agrochemical agents
  • Component in material science applications

Quality Assurance and Safety

Quality is the cornerstone of our manufacturing process. Every production batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We maintain a robust quality management system to ensure that every drum meets the specified purity levels and safety standards. For storage, we recommend keeping the product in a cool, ventilated area away from direct sunlight and moisture. Proper handling ensures the longevity and stability of the chemical properties.

We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requests to suit your specific logistical needs. Our global shipping network ensures timely delivery to laboratories and production facilities worldwide. Partner with us for a reliable supply of high-performance chemical intermediates that meet international regulatory standards. Our team is ready to provide technical support and documentation to facilitate your import and usage processes.