5-Fluoronicotinic Acid

Product Overview

5-Fluoronicotinic Acid is a highly valued fluorinated pyridine derivative extensively utilized in the pharmaceutical and agrochemical industries. As a critical building block, this compound facilitates the introduction of fluorine atoms into complex molecular structures, enhancing metabolic stability and bioavailability in final drug products. Our manufacturing process adheres to strict international quality standards, ensuring consistent performance for research and production scales.

We understand the importance of reliability in supply chain management for fine chemicals. Therefore, we provide comprehensive technical support and documentation, including Certificates of Analysis (COA), to guarantee that every batch meets the specified purity requirements. This product serves as a foundational element for synthesizing various therapeutic agents and functional materials.

Technical Specifications

Physical and Chemical Properties

This compound exhibits distinct physical properties suitable for various organic synthesis reactions. The density is recorded at 1.419g/cm3, with a boiling point of 272.2ºC at 760 mmHg. The flash point is maintained at 118.4ºC, requiring standard safety precautions during handling. The index of refraction is 1.534, confirming its structural integrity. These properties make it compatible with diverse reaction conditions commonly found in medicinal chemistry laboratories.

Industrial Applications

Primarily used as a pharmaceutical intermediate, 5-Fluoronicotinic Acid plays a pivotal role in drug discovery and development. It is frequently employed in the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics. The presence of the fluorine atom at the 5-position of the pyridine ring offers unique electronic effects that can optimize binding affinity to biological targets. Additionally, it finds applications in the development of advanced agrochemicals and functional materials where heterocyclic structures are required.

Quality Assurance and Storage

Quality control is paramount in our production facility. Each batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) to verify identity and purity. We maintain a robust quality management system to ensure traceability and compliance. For storage, the product should be kept in a tightly closed container in a cool, dry, and well-ventilated area. Proper handling procedures must be followed to maintain stability and prevent contamination during long-term storage.