5-Fluoropicolinic acid
- CAS No.107504-08-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
5-Fluoropicolinic acid is a high-purity pharmaceutical intermediate used extensively in organic synthesis. We offer bulk quantities with reliable quality assurance and global shipping.
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Product Overview
5-Fluoropicolinic acid is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. As a derivative of picolinic acid, the introduction of a fluorine atom at the fifth position of the pyridine ring significantly enhances the metabolic stability and lipophilicity of downstream pharmaceutical candidates. This compound is highly valued by research institutions and manufacturing facilities for its reliability in constructing complex molecular architectures.
Our facility produces this intermediate under strict quality control standards to ensure consistency across batches. The presence of the fluorine substituent allows for unique electronic properties that facilitate various coupling reactions, making it an indispensable tool for chemists developing novel therapeutic agents.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 5-Fluoropicolinic acid |
| CAS Number | 107504-08-5 |
| Molecular Formula | C6H4FNO2 |
| Molecular Weight | 141.10 g/mol |
| Appearance | White powder |
| Purity | ≥98.0% |
| Density | 1.419 g/cm3 |
| Boiling Point | 275.1°C at 760 mmHg |
| Flash Point | 120.2°C |
Industrial Applications
This chemical is primarily utilized as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs). The fluorinated pyridine scaffold is a common motif in drugs targeting various therapeutic areas, including oncology, infectious diseases, and central nervous system disorders. Researchers leverage this building block to introduce specific structural features that improve drug bioavailability and binding affinity.
Beyond pharmaceuticals, 5-Fluoropicolinic acid finds applications in agrochemical research and material science. Its robust chemical structure allows it to withstand harsh reaction conditions, making it suitable for multi-step synthesis routes. We support clients with technical data to assist in integrating this material into their specific manufacturing processes.
Quality Assurance and Storage
Every batch of 5-Fluoropicolinic acid undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. We provide a Certificate of Analysis (COA) with each shipment to guarantee compliance with specified standards. Our commitment to quality ensures that your synthesis projects proceed without interruption due to material variability.
For optimal stability, the product should be stored in a tightly closed container in a cool, dry environment. Protection from moisture and direct sunlight is recommended to maintain integrity over time. We offer flexible packaging options, including 25kg drums, to accommodate both laboratory-scale research and large-scale industrial production needs. Contact our sales team for detailed information on bulk pricing and delivery schedules.
