5-Fluoropyridine-2-carbonitrile
- CAS No.327056-62-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Fluoropyridine-2-carbonitrile designed for advanced pharmaceutical synthesis. Available in bulk quantities with full documentation.
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Product Overview
5-Fluoropyridine-2-carbonitrile represents a critical fluorinated heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. As a specialized pharmaceutical intermediate, this compound offers unique reactivity profiles due to the presence of the electron-withdrawing fluorine atom at the fifth position of the pyridine ring. Our manufacturing facility ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for complex drug discovery programs and process development.
The strategic incorporation of fluorine into organic molecules is a well-established technique to enhance metabolic stability, bioavailability, and binding affinity in potential therapeutic agents. This specific nitrile derivative serves as a versatile precursor for various coupling reactions, nucleophilic substitutions, and cyclization processes. Researchers and procurement managers rely on our supply chain for dependable access to this high-value chemical entity.
Key Specifications
We maintain strict quality control protocols throughout the production lifecycle. The following table outlines the typical physical and chemical properties associated with our commercial grade material. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with these specifications.
| Parameter | Specification |
|---|---|
| CAS Number | 327056-62-2 |
| Molecular Formula | C6H3FN2 |
| Molecular Weight | 122.10 g/mol |
| Appearance | White to Off-White Powder |
| Purity | ≥98.0% |
| Melting Point | 35-41 °C |
| Boiling Point | 214.9 °C at 760 mmHg |
| Density | 1.2 ±0.1 g/cm3 |
| Refractive Index | 1.510 |
Industrial Applications
Primarily designated for use as a pharmaceutical intermediate, 5-Fluoropyridine-2-carbonitrile finds application in the synthesis of kinase inhibitors, antiviral agents, and other small molecule drugs. The cyano group provides a handle for further functionalization, such as conversion to amines, tetrazoles, or carboxylic acids, while the fluorine atom modulates the electronic properties of the aromatic system. This dual functionality makes it indispensable for constructing diverse chemical libraries during lead optimization phases.
Beyond human pharmaceuticals, this compound may also serve in the development of agrochemicals and advanced materials where fluorinated pyridine motifs are required. Our technical team supports clients with guidance on safe handling and integration into existing synthesis routes, ensuring smooth scale-up from laboratory to pilot plant operations.
Quality Assurance and Logistics
As a global manufacturer, we understand the importance of supply chain reliability. Our production processes are optimized for industrial purity, minimizing impurities that could interfere with downstream reactions. We offer flexible packaging options, including standard 25 kg drums, to accommodate varying project scales. All products are stored in tightly closed containers within cool, dry environments to maintain stability during transit and storage.
- Consistent batch-to-batch reproducibility
- Full regulatory documentation support
- Secure packaging for international shipping
- Responsive customer service for technical inquiries
For detailed safety information, please refer to the Material Safety Data Sheet (MSDS) provided with your order. We are committed to delivering excellence in every gram, supporting your innovation from early research to commercial manufacturing.
