5-Iodo-2'-deoxycytidine

Product Overview

5-Iodo-2'-deoxycytidine is a specialized halogenated nucleoside analog designed for advanced biochemical research and pharmaceutical development. As a critical building block in the synthesis of modified oligonucleotides, this compound enables precise structural modifications essential for contemporary genetic studies. Our manufacturing process ensures exceptional consistency, making it an ideal choice for laboratories focused on antisense technology and molecular diagnostics.

This modified nucleoside features an iodine substitution at the fifth position of the cytosine ring, which significantly enhances its reactivity for cross-coupling reactions. The stereochemistry is strictly controlled to match the natural 2'-deoxyribose configuration, ensuring compatibility with enzymatic processes and polymerase recognition during oligonucleotide assembly.

Technical Specifications

Applications and Usage

The primary application of 5-Iodo-2'-deoxycytidine lies in the construction of DNA oligomers for structural biology and therapeutic research. It serves as a versatile precursor for photoactivated cross-linking studies, allowing scientists to investigate protein-DNA interactions with high spatial resolution. Furthermore, it is extensively used in the synthesis of other complex modified nucleosides required for semiconductor electrode applications and advanced material science.

• Facilitates structural studies of nucleic acid complexes
• Enables photoactivated cross-linking experiments
• Precursor for 5-ethynylferrocenyl-2'-deoxycytidine synthesis
• Used in developing novel nucleoside analogs for therapeutics
• Supports research in oligonucleotide-based diagnostics

Quality Assurance and Safety

Our facility adheres to rigorous quality control standards to guarantee the integrity of every batch. Each production lot undergoes comprehensive testing via High-Performance Liquid Chromatography (HPLC) to verify purity levels exceeding 99.0%. We provide a complete Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. This commitment to quality ensures reproducibility in your research outcomes and minimizes batch-to-batch variability.

Storage and Handling

To maintain stability and potency, 5-Iodo-2'-deoxycytidine should be stored in a cool, ventilated environment away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, though we offer flexible customization to meet specific logistical requirements. Proper handling protocols should be followed to prevent contamination, ensuring the material remains suitable for sensitive biochemical applications upon arrival.