Intermediates

5-Iodocytidine

  • CAS No.1147-23-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Iodocytidine (CAS 1147-23-5) designed for advanced nucleic acid research and pharmaceutical development.

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Product Technical Details

Product Overview

5-Iodocytidine represents a critical halogenated nucleoside analog utilized extensively within the realm of biochemical research and pharmaceutical development. As a specialized chemical intermediate, this compound serves as a fundamental building block for the synthesis of complex nucleic acid structures and probes. Our manufacturing process ensures that every batch meets rigorous international standards for purity and stability, making it an ideal choice for laboratories focused on genetic interaction studies and medicinal chemistry.

The introduction of an iodine atom at the fifth position of the cytosine ring significantly alters the electronic and steric properties of the molecule. This modification allows researchers to explore unique binding affinities and structural conformations that are not possible with native nucleosides. Consequently, 5-Iodocytidine is indispensable for projects involving DNA labeling, cross-linking studies, and the development of novel antiviral or anticancer agents.

Key Specifications

ParameterValue
CAS Number1147-23-5
Molecular FormulaC9H12IN3O5
Molecular Weight369.11 g/mol
AppearanceWhite powder
Assay (HPLC)≥99.0%
Assay (UV)≥97.0%
Moisture Content≤4%
Heavy Metals≤10ppm

Applications and Benefits

Our clients leverage 5-Iodocytidine for a variety of high-value applications in the life sciences sector. The high purity grade we provide ensures minimal interference in sensitive analytical procedures such as high-performance liquid chromatography and mass spectrometry. Key application areas include:

  • Nucleic Acid Research: Facilitating studies on nucleic acid-protein interactions and structural biology.
  • Pharmaceutical Synthesis: Serving as a key intermediate in the production of modified nucleoside drugs.
  • Chemical Biology: Enabling the creation of site-specific probes for tracking cellular processes.
  • Quality Assurance: Each lot is accompanied by a comprehensive Certificate of Analysis to verify compliance with specified parameters.

Manufacturing and Quality Control

We employ advanced synthetic routes to achieve industrial purity levels that exceed standard market expectations. Our quality control team implements multi-stage testing protocols, including HPLC and UV spectroscopy, to guarantee consistency across all shipments. By maintaining strict control over impurities such as heavy metals and residual solvents, we support our partners in meeting regulatory requirements for research materials. Our facility is optimized for scalable production, allowing us to fulfill both small-scale research orders and large bulk requirements efficiently.

Storage and Handling

To maintain the integrity of 5-Iodocytidine, proper storage conditions are essential. The product should be kept in a cool, ventilated environment away from direct sunlight and moisture sources. Containers must be tightly sealed after each use to prevent degradation. When handling this chemical, standard laboratory safety precautions should be observed, including the use of appropriate personal protective equipment. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions to meet specific logistical needs for global shipping.