Intermediates

5-Iodopyridin-2-amine

  • CAS No.20511-12-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Iodopyridin-2-amine (CAS 20511-12-0) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

5-Iodopyridin-2-amine stands as a pivotal compound within the realm of heterocyclic chemistry, serving as an essential building block for complex molecular architectures. This iodinated pyridine derivative is highly valued in the pharmaceutical and agrochemical industries for its unique reactivity profile. The presence of the iodine atom at the fifth position of the pyridine ring facilitates various cross-coupling reactions, making it an indispensable tool for medicinal chemists and process developers alike.

Our manufacturing facility adheres to rigorous quality standards to ensure that every batch of 5-Iodopyridin-2-amine meets the highest specifications for purity and consistency. We understand the critical nature of raw materials in drug discovery and production, which is why our supply chain is optimized for reliability and speed. Whether for laboratory-scale research or large-scale industrial production, our product provides the foundational quality required for successful synthesis outcomes.

Technical Specifications

We maintain strict control over the physical and chemical properties of this intermediate to guarantee performance in downstream applications. The following table outlines the key parameters verified through our quality assurance protocols.

ParameterSpecification
Chemical Name5-Iodopyridin-2-amine
CAS Number20511-12-0
Molecular FormulaC5H5IN2
Molecular Weight220.01 g/mol
AppearanceBrown solid
Assay≥98.0%
Melting Point128-131°C
Boiling Point293.8°C
Density2.055 g/cm3

Industrial Applications

The primary utility of 5-Iodopyridin-2-amine lies in its role as a versatile intermediate for organic synthesis. It is frequently employed in the construction of biologically active molecules, including kinase inhibitors and other therapeutic agents. The iodine substituent allows for efficient palladium-catalyzed coupling reactions, such as Suzuki-Miyaura or Heck reactions, enabling the introduction of diverse functional groups onto the pyridine scaffold.

Beyond pharmaceuticals, this compound finds application in the development of advanced agrochemicals and functional materials. Researchers utilize this building block to explore structure-activity relationships and optimize lead compounds. Our high-purity grade ensures minimal impurity interference during sensitive reaction steps, thereby improving overall yield and reducing purification burdens.

Quality Assurance and Storage

Quality is the cornerstone of our operation. Each production lot undergoes comprehensive testing using advanced analytical techniques such as HPLC and NMR to confirm identity and purity. We provide a Certificate of Analysis (COA) with every shipment, ensuring full transparency and traceability for our clients.

To maintain stability, 5-Iodopyridin-2-amine should be stored in a cool, ventilated place away from direct sunlight and moisture. We offer flexible packaging options, including standard 25 kg drums, and can customize packaging according to specific customer requirements. Our logistics network supports global shipping, ensuring timely delivery to facilitate your production schedules without interruption.