Intermediates

5-Methoxy-1H-indole-3-carboxylic Acid

  • CAS No.10242-01-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Methoxy-1H-indole-3-carboxylic Acid (CAS 10242-01-0) supplied for pharmaceutical research and organic synthesis applications.

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Product Technical Details

Product Overview

5-Methoxy-1H-indole-3-carboxylic Acid is a specialized organic compound characterized by its indole core structure substituted with a methoxy group at the fifth position. This chemical serves as a vital building block in the realm of advanced medicinal chemistry and complex organic synthesis. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for research and development purposes.

The presence of the carboxylic acid functional group at the third position of the indole ring provides versatile reactivity, allowing chemists to perform various derivatization reactions. These include amidation, esterification, and reduction processes, making it an invaluable precursor for constructing more complex molecular architectures used in pharmaceutical discovery.

Key Specifications

ParameterValue
CAS Number10242-01-0
Molecular FormulaC10H9NO3
Molecular Weight191.183 g/mol
AppearanceLight yellow powder
Assay≥98.0%
Density1.4±0.1 g/cm3
Boiling Point447.6±25.0 °C at 760 mmHg
Flash Point224.5±23.2 °C

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of various pharmaceutical agents. The methoxy substitution enhances the electronic properties of the indole ring, which can be critical for the biological activity of the final drug candidate. Researchers frequently employ this substance in the development of anti-inflammatory agents, cardiovascular medications, and other therapeutic categories where indole scaffolds are prevalent.

Beyond pharmaceuticals, 5-Methoxy-1H-indole-3-carboxylic Acid finds utility in material science and agrochemical research. Its stability and defined reactivity profile make it suitable for creating specialized polymers and functional materials. Our production process ensures that the material is free from unwanted isomers and impurities that could interfere with downstream synthesis steps.

Quality Assurance and Storage

We adhere to rigorous quality management systems to guarantee the integrity of every batch. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity levels and physical constants. Our analytical team utilizes high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify structural identity and purity.

  • Strict contamination control during manufacturing.
  • Batch-to-batch consistency for reliable research outcomes.
  • Comprehensive documentation supporting regulatory compliance.

For optimal stability, this product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper sealing of containers is essential to prevent degradation over time. We offer flexible packaging options, including standard 25 kg drums, to accommodate both laboratory-scale research and larger pilot production needs. Our logistics team ensures safe and timely global delivery while maintaining all necessary safety documentation for chemical transport.