5-Methoxy-7-azaindole
- CAS No.183208-36-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
5-Methoxy-7-azaindole is a high-purity pharmaceutical intermediate used in advanced organic synthesis. We offer bulk quantities with full quality documentation.
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Product Overview
5-Methoxy-7-azaindole represents a sophisticated heterocyclic building block essential for modern medicinal chemistry and pharmaceutical development. As a substituted azaindole derivative, this compound features a pyrrolopyridine scaffold that offers unique electronic and steric properties compared to traditional indole structures. Our manufacturing process ensures consistent quality suitable for complex drug discovery programs and large-scale production needs.
This chemical serves as a critical precursor in the synthesis of various bioactive molecules. The methoxy substitution at the fifth position enhances solubility profiles and metabolic stability, making it a preferred choice for researchers developing kinase inhibitors and other therapeutic agents. We maintain strict quality control protocols to guarantee that every batch meets international standards for purity and performance.
Chemical Properties
The molecular structure of 5-Methoxy-7-azaindole contributes to its versatility in organic synthesis. With a molecular formula of C8H8N2O and a molecular weight of 148.16, it exhibits favorable physical characteristics for handling and processing. The compound demonstrates thermal stability within standard laboratory conditions while remaining reactive enough for further functionalization.
| Parameter | Specification |
|---|---|
| CAS Number | 183208-36-8 |
| Molecular Formula | C8H8N2O |
| Molecular Weight | 148.16 |
| Appearance | White to off-white powder |
| Purity | ≥98.0% |
| Water Content (KF) | ≤0.50% |
| Density | 1.2 ± 0.1 g/cm3 |
| Boiling Point | 314.9 ± 22.0 °C |
| Flash Point | 107.9 ± 12.0 °C |
Industrial Applications
Primarily utilized as a pharmaceutical intermediate, this compound plays a vital role in the construction of novel drug candidates. The azaindole core is frequently employed as a bioisostere for indole in structure-activity relationship studies. Researchers leverage this building block to optimize binding affinity and selectivity in target proteins.
- Development of small molecule inhibitors for oncology treatments.
- Synthesis of anti-inflammatory agents and immunomodulators.
- Construction of complex heterocyclic libraries for high-throughput screening.
- Usage in custom synthesis projects requiring specific substitution patterns.
Our global clientele includes research institutions and pharmaceutical companies seeking reliable supply chains for critical raw materials. The high purity grade ensures minimal impurity interference during downstream reactions, reducing waste and improving overall yield.
Quality Assurance and Storage
We adhere to rigorous quality management systems to maintain product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results against specified parameters. Our analytical methods include HPLC and NMR spectroscopy to verify structural identity and purity levels.
Proper storage is essential to maintain the stability of 5-Methoxy-7-azaindole. The material should be kept in a cool, dry place away from direct light and moisture. Containers must remain tightly sealed when not in use to prevent degradation. We offer flexible packaging options, including 25kg cardboard drums, to suit various logistical requirements. For bulk orders or custom specifications, our technical team is available to discuss tailored solutions that align with your production schedules.
