Intermediates

5-Methoxyindole-2-carboxylic acid

  • CAS No.4382-54-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 5-Methoxyindole-2-carboxylic acid (CAS 4382-54-1) designed for advanced pharmaceutical synthesis and organic research applications with reliable global supply.

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Product Technical Details

Product Overview

5-Methoxyindole-2-carboxylic acid is a specialized organic compound widely recognized for its significant role in modern pharmaceutical chemistry and advanced material synthesis. As a key indole derivative, this substance serves as a critical building block for the development of complex molecular structures. Our manufacturing process ensures that every batch meets stringent quality standards, providing researchers and industrial partners with a reliable foundation for their synthesis projects. The compound features a methoxy substitution at the fifth position of the indole ring, which imparts specific electronic and steric properties valuable in medicinal chemistry.

We understand the importance of consistency in chemical manufacturing. Therefore, our production facilities adhere to rigorous protocols to maintain high levels of purity and structural integrity. This product is particularly valued in the creation of heterocyclic compounds, which are essential components in many therapeutic agents. By choosing our supply, clients gain access to a material that supports efficient reaction pathways and minimizes downstream purification challenges.

Technical Specifications

ParameterSpecification
CAS Number4382-54-1
Molecular FormulaC10H9NO3
Molecular Weight191.183 g/mol
AppearanceLight yellow powder
Assay (Purity)≥98.0%
Melting Point199-201 °C
Density1.4±0.1 g/cm3
Boiling Point447.6±25.0 °C

Industrial Applications

This chemical intermediate is primarily utilized in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). The indole scaffold is a privileged structure in drug discovery, found in numerous medications targeting various physiological pathways. The presence of the carboxylic acid group allows for versatile functionalization, enabling chemists to form amides, esters, and other derivatives crucial for structure-activity relationship (SAR) studies. Additionally, the methoxy group enhances lipophilicity, which can improve the bioavailability of final drug candidates.

Beyond pharmaceuticals, this compound finds applications in agrochemical research and fine chemical production. It serves as a precursor for specialized polymers and organic electronic materials where indole-based conjugation is required. Our clients leverage this material to accelerate their R&D timelines, benefiting from its high reactivity and stability under standard laboratory conditions. We support diverse synthesis routes, ensuring compatibility with both small-scale research and large-scale manufacturing processes.

Quality Assurance and Safety

Quality is the cornerstone of our operation. Each production lot undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a Certificate of Analysis (COA) with every shipment, detailing purity levels and impurity profiles. Our commitment to safety extends to packaging and handling guidelines. While this compound is intended for professional use, we recommend standard laboratory safety practices, including the use of personal protective equipment during handling.

Storage and Packaging

To maintain optimal stability, 5-Methoxyindole-2-carboxylic acid should be stored in a cool, ventilated environment away from direct sunlight and moisture. Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical requirements. Proper storage ensures that the chemical properties remain unchanged over time, guaranteeing performance in your synthesis workflows. For bulk orders or technical inquiries, our team is ready to provide detailed documentation and support.