5-Methyl-1,3-benzodioxole
- CAS No.7145-99-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-Methyl-1,3-benzodioxole (CAS 7145-99-5) designed for pharmaceutical synthesis and organic research applications.
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Product Overview
5-Methyl-1,3-benzodioxole is a specialized organic compound widely recognized for its utility in advanced pharmaceutical synthesis and chemical research. As a key building block, this substance serves as a critical intermediate in the production of complex therapeutic agents. Our facility ensures that every batch meets stringent quality standards, providing researchers and manufacturers with a reliable source of high-purity chemical materials.
This compound features a benzodioxole backbone with a methyl substitution, offering unique reactivity profiles suitable for various organic transformations. It is particularly valued in the development of endothelin receptor antagonists and other specialized medicinal compounds. Our commitment to excellence ensures that clients receive materials that facilitate efficient synthesis pathways and consistent experimental outcomes.
Technical Specifications
We maintain rigorous control over physical and chemical parameters to guarantee performance consistency. The following table outlines the standard specifications for our commercial grade material. Custom specifications may be available upon request for specific research requirements.
| Parameter | Specification |
|---|---|
| CAS Number | 7145-99-5 |
| Molecular Formula | C8H8O2 |
| Molecular Weight | 136.148 g/mol |
| Appearance | Colorless to yellow liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 200.4±30.0 °C at 760 mmHg |
| Flash Point | 76.1±0.0 °C |
Industrial Applications
The primary application of 5-Methyl-1,3-benzodioxole lies in the pharmaceutical sector, where it functions as a vital intermediate. It is specifically utilized in the synthesis of Sitaxentan sodium, a compound investigated for pulmonary arterial hypertension. Beyond this specific use, the chemical structure allows for versatility in heterocyclic chemistry, enabling the creation of diverse molecular architectures required for drug discovery programs.
Chemists leverage this intermediate for its stability and reactivity during multi-step synthesis processes. Its high purity level minimizes side reactions, thereby improving overall yield and reducing downstream purification burdens. This makes it an economical choice for large-scale manufacturing environments where efficiency is paramount.
Quality Assurance and Safety
Quality is the cornerstone of our manufacturing process. Each production lot undergoes comprehensive analysis using advanced chromatographic techniques such as HPLC and GC-MS. We provide a Certificate of Analysis (COA) with every shipment, detailing test results against internal standards. This transparency allows our partners to validate material suitability before integration into their workflows.
- Strict adherence to ISO quality management systems.
- Batch traceability for full supply chain visibility.
- Regular stability testing to ensure shelf-life integrity.
Regarding safety, this chemical should be handled in accordance with standard laboratory safety protocols. It is recommended to store the material in a cool, ventilated area away from direct sunlight and incompatible substances. Proper personal protective equipment, including gloves and eye protection, should be worn during handling to prevent exposure. In case of spills, standard chemical containment procedures should be followed immediately.
Packaging and Logistics
We understand the importance of secure logistics in the chemical industry. Our standard packaging consists of 200 kg drums, designed to protect the integrity of the liquid during transit. However, we offer flexible packaging solutions tailored to customer requirements, ensuring compatibility with your specific storage and handling infrastructure. Global shipping capabilities allow us to serve clients worldwide with reliable delivery schedules.
