Intermediates

5-Methyl-1H-indole-2-carboxylic acid

  • CAS No.10241-97-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity organic synthesis intermediate ideal for pharmaceutical research and development projects requiring reliable indole derivatives.

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Product Technical Details

Product Overview

5-Methyl-1H-indole-2-carboxylic acid represents a critical building block in the realm of advanced organic synthesis and medicinal chemistry. As a specialized indole derivative, this compound serves as a foundational element for constructing complex heterocyclic structures found in numerous pharmaceutical candidates. Our facility produces this chemical intermediate with a steadfast commitment to quality, ensuring that every batch meets rigorous international standards for purity and consistency.

The molecular architecture of this compound, characterized by the indole core substituted with a methyl group and a carboxylic acid moiety, provides unique reactivity profiles. This makes it an invaluable asset for chemists engaged in the development of novel therapeutic agents, agrochemicals, and functional materials. We understand the demands of modern research laboratories and production lines, which is why we prioritize stability and reproducibility in every shipment.

Technical Specifications

To guarantee performance in downstream applications, we maintain strict control over physical and chemical parameters. The following table outlines the key specifications associated with CAS 10241-97-1:

ParameterSpecification
Chemical Name5-Methyl-1H-indole-2-carboxylic acid
CAS Number10241-97-1
Molecular FormulaC10H9NO2
Molecular Weight175.184 g/mol
AppearanceWhite to off-white powder
Assay (Purity)≥97.0%
Melting Point236-238°C (dec.)
Density1.3±0.1 g/cm3
Boiling Point421.2±25.0 °C at 760 mmHg

Applications in Organic Synthesis

This indole carboxylic acid derivative is predominantly utilized as a key intermediate in the synthesis of biologically active compounds. Its structural features allow for various functionalization strategies, including amidation, esterification, and cross-coupling reactions. Researchers frequently employ this material in the exploration of kinase inhibitors, anti-inflammatory agents, and other small molecule drugs targeting specific biological pathways.

Beyond pharmaceuticals, the compound finds utility in the creation of specialized polymers and organic electronic materials where indole units confer specific electronic properties. The high purity level ensures minimal side reactions during sensitive synthetic steps, thereby improving overall yield and reducing purification burdens in multi-step synthesis routes.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing process. Each production lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is provided with every order, documenting all test results against established specifications. This transparency allows our clients to maintain their own quality management systems with confidence.

Proper storage is essential to maintain the integrity of the product. We recommend storing the material in a cool, ventilated place away from direct sunlight and moisture. The packaging consists of durable drums capable of protecting the contents during international transit. For large-scale requirements, we offer flexible packaging solutions tailored to specific logistical needs.

Why Choose Our Supply Chain

As a global manufacturer, we combine technical expertise with logistical efficiency. Our clients benefit from competitive bulk pricing, reliable lead times, and dedicated technical support. Whether you are scaling up from laboratory research to pilot production, our team is equipped to support your supply chain requirements with consistency and professionalism.