5-Trifluoromethyl-1H-indole-2-carboxylic acid
- CAS No.496946-78-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 5-Trifluoromethyl-1H-indole-2-carboxylic acid designed for advanced organic synthesis. Reliable supply with comprehensive quality documentation for industrial scaling.
Request Bulk PricingProduct Technical Details
Product Overview
5-Trifluoromethyl-1H-indole-2-carboxylic acid is a specialized fluorinated heterocyclic compound widely utilized in the field of medicinal chemistry and organic synthesis. As a key building block, this indole derivative offers unique structural properties that enhance the metabolic stability and lipophilicity of target molecules. Our manufacturing process ensures consistent quality suitable for research and development phases as well as large scale production requirements.
The incorporation of the trifluoromethyl group at the 5-position of the indole ring significantly influences the electronic characteristics of the molecule. This makes it an invaluable intermediate for the development of novel pharmaceutical agents and agrochemicals. We prioritize strict quality control measures to deliver material that meets rigorous international standards.
Technical Specifications
Our production facility adheres to Good Manufacturing Practices to guarantee the integrity of every batch. The following table outlines the critical physical and chemical parameters verified during our quality assurance process.
| Parameter | Specification |
|---|---|
| CAS Number | 496946-78-2 |
| Molecular Formula | C10H6F3NO2 |
| Molecular Weight | 229.155 |
| Appearance | Light yellow to yellow solid |
| Assay | ≥95.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 402.5±40.0 °C at 760 mmHg |
| Flash Point | 197.2±27.3 °C |
Quality Assurance
Quality is the cornerstone of our chemical supply chain. Each batch of 5-Trifluoromethyl-1H-indole-2-carboxylic acid undergoes comprehensive analytical testing using advanced instrumentation such as HPLC and NMR. We provide a Certificate of Analysis with every shipment to ensure transparency and traceability. Our commitment to industrial purity means minimizing impurities that could interfere with downstream synthesis reactions.
We maintain a robust supply chain capable of handling bulk orders without compromising on delivery timelines. Our technical team is available to support customers with specific packaging requirements or custom synthesis needs. Safety data sheets and handling guidelines are provided to ensure safe storage and usage within your facility.
Applications in Organic Synthesis
This fluorinated indole derivative serves as a versatile precursor in the construction of complex molecular architectures. Common applications include:
- Synthesis of kinase inhibitors and other therapeutic candidates
- Development of agrochemical active ingredients
- Creation of functional materials with specific electronic properties
- Use as a reference standard in analytical chemistry
The stability of the carboxylic acid moiety allows for various derivatization reactions including amidation and esterification. This flexibility makes it a preferred choice for chemists exploring structure-activity relationships.
Storage and Safety Information
To maintain optimal quality, store this product in a cool and ventilated area away from direct sunlight and moisture. Keep containers tightly closed when not in use. Always follow standard laboratory safety protocols when handling chemical intermediates. Appropriate personal protective equipment should be worn during transfer and weighing operations. For detailed safety information please refer to the provided Safety Data Sheet.
