5-(Trifluoromethyl)picolinonitrile
- CAS No.95727-86-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 5-(Trifluoromethyl)picolinonitrile (CAS 95727-86-9) for organic synthesis. Reliable supply with ≥98.0% assay and strict quality control.
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Product Overview
5-(Trifluoromethyl)picolinonitrile is a highly valued fluorinated heterocyclic compound widely utilized in modern organic synthesis. As a critical building block, this substance features a pyridine ring substituted with a trifluoromethyl group and a nitrile functionality. These structural characteristics impart unique electronic and steric properties, making it an essential precursor for the development of advanced pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity levels to meet the rigorous demands of research and industrial production.
The incorporation of fluorine atoms into organic molecules is a strategic approach in medicinal chemistry to enhance metabolic stability and bioavailability. This specific nitrile derivative serves as a versatile intermediate for constructing complex molecular architectures. We prioritize safety and compliance throughout our supply chain, ensuring that all materials are handled according to international chemical safety standards.
Key Features and Advantages
- High Chemical Purity: Assay levels consistently maintained at or above 98.0 percent to minimize side reactions.
- Stable Supply Chain: Robust production capacity ensures timely delivery for large-scale projects.
- Strict Quality Control: Every batch undergoes comprehensive testing including HPLC and NMR analysis.
- Flexible Packaging: Available in standard drums or customized containers based on client requirements.
- Technical Support: Dedicated team available to assist with application guidance and documentation.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 95727-86-9 |
| Molecular Formula | C7H3F3N2 |
| Molecular Weight | 172.107 g/mol |
| Appearance | Off-white solid |
| Assay | ≥98.0% |
| Moisture Content | ≤0.5% |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 232.3±40.0 °C at 760 mmHg |
| Flash Point | 94.3±27.3 °C |
Industrial Applications
This fluorinated pyridine derivative is primarily employed as a key intermediate in the synthesis of various bioactive compounds. In the pharmaceutical sector, it facilitates the creation of novel therapeutic candidates targeting diverse biological pathways. The trifluoromethyl group enhances lipophilicity, which is often crucial for drug membrane permeability. Additionally, it finds application in the agrochemical industry for developing crop protection agents that require high environmental stability.
Researchers utilize this building block for cross-coupling reactions, nucleophilic substitutions, and heterocycle formations. Its reactivity profile allows for versatile functionalization, enabling chemists to explore broad chemical space during lead optimization phases. We support both academic research institutions and commercial enterprises with reliable material supply.
Storage and Handling
To maintain product integrity, 5-(Trifluoromethyl)picolinonitrile should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent contamination or degradation. Standard industrial safety protocols apply during handling, including the use of appropriate personal protective equipment. We recommend consulting the safety data sheet for detailed hazard information and emergency measures.
Our commitment to excellence extends beyond product quality to include comprehensive documentation. Certificates of Analysis are provided with every shipment to verify compliance with specified parameters. For bulk orders or specific technical inquiries, our sales team is ready to provide competitive pricing and logistical solutions tailored to your operational needs.
