6,7-Bis(2-Methoxyethoxy)-1H-Quinazolin-4-One

Product Overview

6,7-Bis(2-Methoxyethoxy)-1H-Quinazolin-4-One is a specialized pharmaceutical intermediate characterized by its high chemical stability and precise molecular structure. As a critical building block in the synthesis of Erlotinib, this quinazolinone derivative plays an indispensable role in the production of targeted kinase inhibitors used in oncology therapeutics. Our manufacturing facility adheres to strict quality management systems to ensure every batch meets the rigorous demands of modern pharmaceutical development.

We understand that consistency in molecular weight and purity is paramount for downstream reaction efficiency. Therefore, this product is synthesized using advanced organic chemistry techniques that minimize impurities and maximize yield. The compound features a distinct quinazolinone core substituted with methoxyethoxy groups, providing the necessary reactivity for subsequent coupling reactions in API manufacturing.

Technical Specifications

Our quality control laboratory employs state-of-the-art analytical instrumentation, including HPLC and NMR, to verify the identity and purity of each production lot. The physical properties are tightly controlled to ensure compatibility with standard industrial processing conditions. Below are the key technical parameters for this chemical intermediate:

Quality Assurance and Manufacturing

As a global manufacturer, we prioritize transparency and reliability. Every shipment is accompanied by a Certificate of Analysis (COA) that details the test results for purity, residual solvents, and heavy metals. Our production lines are designed to handle bulk orders efficiently while maintaining the integrity of the chemical structure. We implement a multi-stage purification process to achieve the specified purity level of 99.0% or higher, ensuring that downstream synthesis steps are not compromised by impurities.

Our team of chemists is available to provide technical support regarding the synthesis route and manufacturing process. We can accommodate custom synthesis requests for specific purity grades or packaging configurations based on project requirements. This flexibility allows research institutions and pharmaceutical companies to streamline their supply chain for kinase inhibitor precursors.

Application and Usage

This intermediate is primarily utilized in the pharmaceutical industry for the production of Erlotinib, a tyrosine kinase inhibitor. It serves as a key scaffold in the construction of the final active pharmaceutical ingredient. Due to its specific substitution pattern, it offers excellent reactivity profiles for nucleophilic substitution and condensation reactions. Researchers and process chemists value this compound for its consistent performance in scale-up operations.

Storage and Handling

To maintain optimal quality, 6,7-Bis(2-Methoxyethoxy)-1H-Quinazolin-4-One should be stored in a cool, ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, which are sealed to prevent contamination during transit. We also offer flexible packaging solutions to meet specific customer logistics needs. Proper handling procedures should be followed in accordance with local safety regulations and material safety data sheets.