6,7-Dimethoxy-4-hydroxyquinoline
- CAS No.13425-93-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6,7-Dimethoxy-4-hydroxyquinoline (CAS 13425-93-9), a key pharmaceutical intermediate for Tivozanib synthesis, manufactured to stringent quality standards.
Request Bulk PricingProduct Technical Details
Product Overview
6,7-Dimethoxy-4-hydroxyquinoline is a high-value quinoline derivative widely employed as a critical building block in the synthesis of advanced pharmaceutical intermediates. With a molecular formula of C11H11NO3 and a molecular weight of 205.21 g/mol, this compound exhibits excellent reactivity and selectivity in heterocyclic chemistry, making it indispensable in modern medicinal chemistry workflows.
Specifications
| Appearance | Yellow to off-white crystalline powder |
|---|---|
| Purity (HPLC) | ≥98.0% |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.5% |
| Any Single Impurity | ≤0.5% |
| Total Impurities | ≤1.0% |
| Density | 1.206 g/cm³ |
| Melting Point | 30°C |
| Boiling Point | 355.3°C |
| Flash Point | 168.7°C |
Industrial Applications
This compound serves primarily as a specialized intermediate in the production of Tivozanib, a potent tyrosine kinase inhibitor used in oncology therapeutics. Its well-defined substitution pattern enables efficient regioselective functionalization during multi-step syntheses.
- Enables streamlined access to complex quinoline-based active pharmaceutical ingredients (APIs)
- Manufactured under strict GMP-aligned conditions to ensure batch-to-batch consistency
- Suitable for scale-up in commercial pharmaceutical manufacturing environments
Packaging is typically provided in 25 kg drums, with custom options available upon request. The product should be stored in a cool, dry, and well-ventilated area, protected from moisture and direct sunlight. Please note that distribution may be restricted in jurisdictions where relevant patents are in force.
