Intermediates

6-Bromo-2,3-Dihydro-4H-Chromen-4-One

  • CAS No.49660-57-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Bromo-2,3-Dihydro-4H-Chromen-4-One (CAS 49660-57-3) designed for pharmaceutical synthesis. Reliable supply with ≥98.0% assay for advanced organic research.

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Product Technical Details

Product Overview

6-Bromo-2,3-Dihydro-4H-Chromen-4-One represents a critical specialized building block within the realm of advanced organic synthesis. As a brominated derivative of the chromanone scaffold, this compound serves as an essential precursor for the development of complex pharmaceutical architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research laboratories and industrial scale-up projects requiring high reliability and structural integrity.

The presence of the bromine substituent at the sixth position significantly enhances the reactivity of the molecule, facilitating various cross-coupling reactions and nucleophilic substitutions. This versatility makes it a valuable asset in the construction of heterocyclic systems found in numerous therapeutic candidates. We prioritize purity and chemical stability, delivering a product that meets rigorous international standards for fine chemical intermediates used in drug discovery.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. Each batch undergoes comprehensive analytical testing using advanced chromatography and spectroscopy methods to verify identity and purity levels. The following table outlines the key physicochemical properties associated with this material, ensuring transparency for our procurement partners:

ParameterValue
CAS Number49660-57-3
Molecular FormulaC9H7BrO2
Molecular Weight227.055 g/mol
AppearanceWhite powder
Assay≥98.0%
Boiling Point336.6±42.0 °C
Density1.6±0.1 g/cm3
Flash Point157.4±27.9 °C

Industrial Applications

This chromanone derivative is primarily utilized as a pharmaceutical intermediate in the synthesis of bioactive molecules. Its robust chemical structure allows it to withstand various reaction conditions while providing a reliable handle for further functionalization. Medicinal chemists frequently employ this compound in the synthesis of heterocyclic drug candidates targeting various physiological pathways. The high purity level ensures minimal side reactions during downstream processing, thereby improving overall yield and reducing purification costs in multi-step synthesis.

  • Serves as a key starting material for heterocyclic drug synthesis.
  • Utilized in structure-activity relationship (SAR) studies.
  • Compatible with palladium-catalyzed coupling reactions.
  • Ideal for scaling up from laboratory to pilot plant production.
  • Supports development of novel therapeutic agents.

Quality Assurance and Logistics

We maintain a strict quality management system to ensure that every drum of 6-Bromo-2,3-Dihydro-4H-Chromen-4-One meets the specified assay requirements. Certificate of Analysis (COA) documents are provided with every shipment to verify compliance. To maintain optimal stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures include using appropriate personal protective equipment during weighing and transfer operations.

We offer flexible packaging options, including standard 25 kg drums, which can be customized according to specific customer logistics requirements. Our global supply chain ensures timely delivery while maintaining the integrity of the chemical throughout transit. Partner with us for reliable supply chain solutions and competitive bulk pricing on high-quality chemical intermediates.