Intermediates

6-Bromo-2-Chloro-3-Fluoropyridine

  • CAS No.1211591-93-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Bromo-2-Chloro-3-Fluoropyridine designed for advanced pharmaceutical and agrochemical synthesis workflows.

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Product Technical Details

Product Overview

6-Bromo-2-Chloro-3-Fluoropyridine is a highly specialized halogenated heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern on the pyridine ring, this molecule offers distinct reactivity profiles that are essential for constructing complex pharmaceutical and agrochemical architectures. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream chemical processes.

The strategic placement of bromine, chlorine, and fluorine atoms on the pyridine core allows for selective nucleophilic substitution and cross-coupling reactions. This versatility makes it an invaluable asset for research and development teams focused on creating novel active pharmaceutical ingredients (APIs) or high-performance crop protection agents. We understand the demanding requirements of industrial chemistry and provide material that meets rigorous specifications.

Technical Specifications

ParameterValue
Chemical Name6-Bromo-2-Chloro-3-Fluoropyridine
CAS Number1211591-93-3
Molecular FormulaC5H2BrClFN
Molecular Weight210.43 g/mol
Purity≥98.0%
AppearanceNot specified

Chemical Properties and Reactivity

The presence of multiple halogen substituents significantly influences the electronic properties of the pyridine ring. The fluorine atom at the 3-position provides metabolic stability in biological contexts, while the bromine and chlorine atoms serve as excellent leaving groups for palladium-catalyzed coupling reactions such as Suzuki, Heck, or Buchwald-Hartwig aminations. This multi-functional capability enables chemists to introduce diverse functional groups at specific positions with high regioselectivity.

Handling this compound requires adherence to standard laboratory safety protocols for halogenated organic materials. It should be processed in well-ventilated areas using appropriate personal protective equipment. The stability of the compound under standard storage conditions ensures a long shelf life, provided it is kept away from moisture and strong oxidizing agents.

Industrial Applications

This intermediate finds extensive utility across several high-value sectors. In the pharmaceutical industry, it is utilized as a key precursor for synthesizing heterocyclic drugs targeting various therapeutic areas. The agrochemical sector leverages this molecule for developing next-generation pesticides and herbicides that require specific bioactivity profiles. Additionally, it serves as a valuable component in the synthesis of specialized dyes and fragrance compounds where unique aromatic structures are necessary.

  • Pharmaceutical Intermediate for API synthesis
  • Agrochemical precursor for pesticide development
  • Building block for specialty dyes and fragrances
  • Research chemical for organic methodology studies

Quality Assurance and Packaging

We maintain a robust quality management system to guarantee the integrity of every batch. Each production lot undergoes comprehensive analysis using advanced techniques such as HPLC and NMR spectroscopy to verify purity and structural identity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified standards.

Standard packaging consists of 25 kg drums, ensuring safe transport and handling. Custom packaging solutions are available to meet specific client logistics requirements. Storage recommendations include keeping the containers tightly closed in a cool, dry, and light-resistant environment to preserve product quality over time. Our global supply chain capabilities ensure timely delivery to manufacturers worldwide.