Intermediates

6-Bromo-2-chloropyridin-3-amine

  • CAS No.169833-70-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Bromo-2-chloropyridin-3-amine intermediate for pharmaceutical and agrochemical synthesis. Available in bulk with full documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

6-Bromo-2-chloropyridin-3-amine represents a highly versatile halogenated heterocyclic building block essential for modern organic synthesis. As a specialized pyridine derivative, this compound features distinct reactive sites at the bromine and chlorine positions, allowing for selective cross-coupling reactions and nucleophilic substitutions. Our manufacturing process ensures exceptional consistency, making it an ideal candidate for complex molecule construction in research and industrial settings.

The strategic placement of halogen atoms on the pyridine ring provides chemists with significant flexibility during synthetic route design. This material is particularly valued in medicinal chemistry programs where precise structural modifications are required to optimize biological activity. We maintain rigorous quality control standards to guarantee that every batch meets the demanding specifications required for downstream processing.

Technical Specifications

Quality assurance is paramount in the production of fine chemical intermediates. Our facility utilizes advanced analytical instrumentation to verify identity and purity levels. The following table outlines the key physical and chemical parameters associated with this product grade.

ParameterSpecification
CAS Number169833-70-9
Molecular FormulaC5H4BrClN2
Molecular Weight207.46 g/mol
AppearanceWhite Crystalline Powder
Purity≥99.0%
Density1.835 g/cm3
Boiling Point302.45 ºC at 760 mmHg
Flash Point136.72 ºC

In addition to standard parameters, we provide comprehensive Certificate of Analysis (COA) documentation with every shipment. This includes detailed data on residual solvents, heavy metals, and related substances to ensure compliance with international regulatory frameworks.

Industrial Applications

This pyridine-based intermediate serves as a critical precursor across multiple high-value sectors. In the pharmaceutical industry, it is frequently employed in the synthesis of kinase inhibitors and other therapeutic agents targeting neurological or oncological pathways. The dual halogen functionality enables sequential functionalization, which is crucial for building complex pharmacophores.

Beyond human health applications, this compound finds extensive use in agrochemical development. It acts as a key building block for novel pesticide formulations designed to enhance crop protection efficacy. Additionally, it is utilized in the production of specialized dyes and flavor compounds where specific heterocyclic structures are required to achieve desired colorimetric or organoleptic properties. Our global supply chain supports diverse manufacturing needs from pilot scale to commercial production.

Storage and Handling

Proper storage conditions are essential to maintain the stability and integrity of 6-Bromo-2-chloropyridin-3-amine. The material should be preserved in well-closed, light-resistant, and airtight containers to prevent degradation from moisture or oxidative exposure. We recommend storing the product in a cool, dry environment away from incompatible substances such as strong oxidizing agents.

Safety during handling is a top priority. Personnel should utilize appropriate personal protective equipment including gloves and eye protection when manipulating this chemical. In case of spillage, standard hazardous material containment procedures should be followed. Our technical support team is available to provide detailed safety data sheets and guidance on best practices for integration into your specific manufacturing processes.