6-Bromo-7H-purine
- CAS No.767-69-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 6-Bromo-7H-purine intermediate for pharmaceutical synthesis. Available in bulk with comprehensive quality documentation.
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Product Overview
6-Bromo-7H-purine is a highly specialized heterocyclic compound that serves as a fundamental building block in the synthesis of advanced pharmaceutical agents. As a brominated purine derivative, this chemical intermediate plays a pivotal role in medicinal chemistry, particularly in the development of kinase inhibitors and nucleoside analogues. Our facility produces this compound under strict quality control protocols to ensure it meets the rigorous demands of modern drug discovery and development pipelines.
The molecular structure of 6-Bromo-7H-purine allows for versatile functionalization, making it an indispensable reagent for organic synthesis. Researchers and process chemists value this material for its reactivity and stability, which facilitate efficient coupling reactions and structural modifications. We are committed to supplying this critical intermediate with consistent quality to support global pharmaceutical innovation.
Technical Specifications
Quality assurance is paramount in the production of pharmaceutical intermediates. Each batch of 6-Bromo-7H-purine undergoes comprehensive analytical testing to verify identity, purity, and physical properties. The following table outlines the key technical parameters that define our product standard:
| Parameter | Specification |
|---|---|
| CAS Number | 767-69-1 |
| Molecular Formula | C5H3BrN4 |
| Molecular Weight | 199.01 g/mol |
| Appearance | White to yellow powder |
| Assay (HPLC) | ≥98.0% |
| Melting Point | >300°C |
| Density | 2.036 g/cm³ |
| Refractive Index | 1.767 |
Industrial Applications
This purine derivative is primarily utilized as a key intermediate in the manufacturing of complex therapeutic molecules. It is notably employed in the synthesis pathway of idelalisib and related phosphoinositide 3-kinase (PI3K) inhibitors. Beyond oncology applications, 6-Bromo-7H-purine finds utility in the creation of antiviral agents and immunomodulators. Its high purity profile ensures minimal impurity carryover into final drug substances, which is critical for regulatory compliance and patient safety.
- Essential for synthesizing kinase inhibitors.
- Used in nucleoside analogue development.
- Supports research in antiviral therapeutics.
- Ideal for custom organic synthesis projects.
Quality And Manufacturing
Our production facility adheres to international quality management standards. We employ advanced chromatographic techniques, including High-Performance Liquid Chromatography (HPLC), to guarantee assay accuracy. Every shipment is accompanied by a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) to provide full transparency. Our technical team is available to assist with customization requests and scale-up support for large-volume requirements.
Packaging And Storage
To maintain product integrity during transit and storage, 6-Bromo-7H-purine is packaged in secure 25 kg drums. Custom packaging solutions are available upon request to suit specific logistical needs. The material should be stored in a cool, well-ventilated area away from direct sunlight and moisture. Proper storage conditions ensure the chemical stability and longevity of the product, preserving its reactivity for future synthesis campaigns. We offer global shipping capabilities to ensure timely delivery to our partners worldwide.
