Intermediates

6-Chloro-2-picoline

  • CAS No.18368-63-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Chloro-2-picoline liquid for organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

6-Chloro-2-picoline is a specialized heterocyclic organic compound widely recognized for its versatility in advanced chemical synthesis. As a chlorinated derivative of picoline, this substance features a pyridine ring structure with specific substitution patterns that enhance its reactivity in nucleophilic substitution reactions. Our facility produces this intermediate with stringent quality controls to ensure consistency across batches, making it an ideal choice for research and industrial-scale manufacturing processes.

The compound is supplied as a colorless to light yellow liquid, offering excellent solubility in common organic solvents. Its physical properties, including a defined boiling point and density, make it suitable for various reaction conditions requiring precise thermal management. We prioritize the delivery of high-purity materials to support the development of complex molecular architectures in the pharmaceutical and agrochemical sectors.

Technical Specifications

ParameterValue
CAS Number18368-63-3
Molecular FormulaC6H6ClN
Molecular Weight127.572 g/mol
AppearanceColorless to light yellow liquid
Assay (Purity)≥98.0%
Density1.2±0.1 g/cm3
Boiling Point183.5±0.0 °C at 760 mmHg
Flash Point73.9±0.0 °C
Refractive Index1.527

Industrial Applications

This chemical intermediate serves as a critical building block in the synthesis of diverse organic compounds. Its primary application lies in the construction of more complex heterocyclic systems used in medicinal chemistry and material science. The chloro group at the second position of the pyridine ring allows for efficient coupling reactions, facilitating the creation of novel derivatives with specific biological or physical properties.

Manufacturers utilize 6-Chloro-2-picoline in the production of fine chemicals, catalysts, and specialized polymers. Its stability and reactivity profile make it a preferred starting material for processes requiring high selectivity. By integrating this intermediate into your synthesis route, you can achieve improved yields and reduced impurity levels in downstream products.

Quality Assurance and Safety

We adhere to rigorous quality assurance protocols to maintain the integrity of our products. Each batch undergoes comprehensive testing using advanced analytical techniques such as gas chromatography and nuclear magnetic resonance spectroscopy. A Certificate of Analysis (COA) is provided with every shipment, documenting key parameters including purity, identity, and physical constants.

Safety is paramount in handling this material. It should be stored in a cool, ventilated place away from incompatible substances. Personnel must wear appropriate personal protective equipment, including chemical-resistant gloves and eye protection, during handling operations. In case of spills, standard chemical containment procedures should be followed immediately to ensure workplace safety and environmental compliance.

Packaging and Logistics

To ensure safe transport and storage, 6-Chloro-2-picoline is packaged in durable drums capable of holding 200 kg per unit. Custom packaging solutions are available upon request to meet specific logistical requirements. Our global shipping network ensures timely delivery to laboratories and manufacturing sites worldwide, supported by detailed documentation for customs clearance and regulatory compliance.