6-Chloro-5-methylpyridin-3-amine
- CAS No.38186-82-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Chloro-5-methylpyridin-3-amine (CAS 38186-82-2), a key pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
Request Bulk PricingProduct Technical Details
Product Overview
6-Chloro-5-methylpyridin-3-amine is a high-value pyridine derivative widely employed as a building block in the synthesis of complex active pharmaceutical ingredients (APIs) and specialty agrochemical compounds. With its dual functional groups—an aromatic amine and a chlorine substituent—it offers versatile reactivity for cross-coupling, nucleophilic substitution, and heterocyclic elaboration strategies.
Specifications
| Molecular Formula | C6H7ClN2 |
|---|---|
| Molecular Weight | 142.59 g/mol |
| Density | 1.3 ± 0.1 g/cm³ |
| Boiling Point | 304.7 ± 37.0 °C at 760 mmHg |
| Flash Point | 138.1 ± 26.5 °C |
| Appearance | Light brown crystalline solid |
| Assay | ≥98.0% |
Industrial Applications
This compound serves primarily as a critical intermediate in multi-step synthetic routes within the pharmaceutical and crop protection industries. Its structural motif enables efficient construction of fused heterocycles and functionalized pyridine scaffolds found in numerous bioactive molecules.
- Ideal for Suzuki, Buchwald-Hartwig, and other transition-metal-catalyzed transformations
- Used in the development of kinase inhibitors and other targeted therapeutics
- Suitable for scale-up under GMP-compliant manufacturing conditions
Stored in a cool, well-ventilated area away from incompatible materials, 6-Chloro-5-methylpyridin-3-amine is typically supplied in 25 kg drums or customized packaging to meet client logistics requirements.
