Intermediates

6-Chloroguanine

  • CAS No.10310-21-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

6-Chloroguanine is a high-purity pharmaceutical intermediate essential for antiviral drug synthesis. We offer bulk quantities with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

6-Chloroguanine, also known chemically as 2-Amino-6-Chloropurine, is a critical purine derivative utilized extensively in the pharmaceutical and fine chemical industries. As a key building block in organic synthesis, this compound serves as a foundational precursor for the development of various nucleoside analogs and antiviral medications. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream manufacturing processes.

The molecular structure of 6-Chloroguanine allows for versatile chemical modifications, making it indispensable for medicinal chemists focused on creating novel therapeutic agents. We prioritize the delivery of high-purity materials that meet or exceed international pharmacopoeia standards, supporting our partners in achieving regulatory compliance for their final drug products.

Technical Specifications

Quality is the cornerstone of our manufacturing process. Each batch of 6-Chloroguanine undergoes rigorous analytical testing using advanced instrumentation such as High-Performance Liquid Chromatography (HPLC) and Infrared Spectroscopy (IR). The following table outlines the standard specification parameters guaranteed for our commercial-grade supply:

ParameterSpecification
CAS Number10310-21-1
Molecular FormulaC5H4ClN5
Molecular Weight169.57 g/mol
AppearanceOff-white to yellow powder
Assay (HPLC)≥98.0%
Loss on Drying≤0.5%
Residue on Ignition≤0.1%
Single Impurity≤0.3%
Total Impurities≤3.0%

Industrial Applications

The primary application of 6-Chloroguanine lies in the synthesis of antiviral pharmaceuticals. It acts as a vital intermediate in the production pathway of Famciclovir, a well-known antiviral prodrug used to treat herpes virus infections. Beyond this specific application, the compound is utilized in the research and development of new purine-based therapeutics targeting various viral and oncological indications.

Our clients leverage this chemical building block for multiple purposes including:

  • Synthesis of nucleoside analogs for antiviral therapy
  • Development of proprietary pharmaceutical formulations
  • Chemical research in heterocyclic compound modification
  • Production of high-value fine chemical intermediates

Quality Assurance and Storage

We maintain a robust quality assurance framework that covers every stage of production, from raw material sourcing to final packaging. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. This transparency ensures that our customers can integrate our materials into their supply chains with full confidence.

Proper storage is essential to maintain the stability and integrity of 6-Chloroguanine. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent contamination or degradation. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions based on specific customer logistics requirements. Our global distribution network ensures timely delivery while maintaining the required storage conditions throughout transit.