6-(Chloromethyl)-11H-benzo[c][1]benzazepine
- CAS No.21535-44-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of Epinastine. Available in bulk quantities with strict quality control and reliable global supply.
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Product Overview
6-(Chloromethyl)-11H-benzo[c][1]benzazepine is a specialized heterocyclic organic compound serving as a critical building block in modern pharmaceutical synthesis. This chemical entity is predominantly utilized as a key intermediate in the production of Epinastine and its various salt forms, including hydrobromide and hydrochloride variants. As a chloromethyl derivative, it possesses high reactivity suitable for nucleophilic substitution reactions, making it an invaluable asset for medicinal chemists developing antihistamine therapies.
Our manufacturing facility adheres to rigorous quality management systems to ensure every batch meets stringent purity specifications. We understand the importance of consistency in pharmaceutical supply chains, which is why our production processes are optimized for stability and reproducibility. This compound is supplied as an off-white powder, facilitating easy handling and integration into downstream synthesis workflows.
Technical Specifications
The following table outlines the key physical and chemical properties verified through our internal quality control laboratories. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to validate these parameters.
| Parameter | Specification |
|---|---|
| CAS Number | 21535-44-4 |
| Molecular Formula | C15H12ClN |
| Molecular Weight | 241.72 g/mol |
| Appearance | Off-white powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.19 g/cm3 |
| Boiling Point | 351°C at 760 mmHg |
| Flash Point | 166.1°C |
| Refractive Index | 1.625 |
Industrial Applications
The primary application of this benzazepine derivative lies within the pharmaceutical sector, specifically targeting the synthesis of allergic conjunctivitis medications. It acts as a precursor molecule that enables the construction of the complex tricyclic structure found in Epinastine. Beyond its primary use, this intermediate may also serve as a research chemical for exploring novel heterocyclic frameworks in organic synthesis.
- Essential intermediate for Epinastine API production
- Used in the synthesis of Epinastine hydrobromide and hydrochloride
- Suitable for custom organic synthesis projects
- High reactivity for nucleophilic substitution reactions
Quality Assurance and Storage
We maintain a robust quality assurance protocol that includes raw material screening, in-process controls, and final product testing. Our commitment to industrial purity ensures that impurities are minimized, reducing the burden on downstream purification steps for our clients. To maintain product integrity, proper storage conditions are essential.
This chemical should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation or contamination. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements based on specific logistical needs. Our global distribution network ensures timely delivery while maintaining compliance with international shipping regulations for chemical substances.
