Intermediates

6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole

  • CAS No.84163-77-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of antipsychotic agents. Available in bulk with comprehensive COA.

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Product Technical Details

Product Overview

6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole is a specialized organic compound widely recognized for its critical role in modern pharmaceutical synthesis. As a key structural building block, this chemical intermediate features a robust benzisoxazole core substituted with a fluorine atom and a piperidine ring. These structural elements contribute to its unique reactivity and stability, making it an essential component in the manufacturing of complex therapeutic agents. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream chemical processes.

The molecular architecture of this substance allows for versatile coupling reactions, which are fundamental in constructing larger active pharmaceutical ingredients. We prioritize the delivery of materials that meet rigorous international standards, supporting research and production teams in achieving their synthesis goals efficiently. Our commitment to excellence ensures that every batch provides the foundational purity required for high-stakes chemical manufacturing.

Technical Specifications

ParameterValue
CAS Number84163-77-9
Molecular FormulaC12H13FN2O
Molecular Weight220.243 g/mol
AppearanceAlmost white to yellow powder
Assay (HPLC)≥98.0% - 102.0%
Melting Point59-62 °C
Boiling Point359.0±42.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point170.9±27.9 °C
Residue on Ignition≤0.5%
Total Impurities≤1.0%

Quality Assurance and Handling

Quality is the cornerstone of our manufacturing process. Each production lot of 6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole undergoes comprehensive analytical testing using high-performance liquid chromatography and other advanced spectroscopic methods. This ensures that the assay purity and impurity profiles remain within the specified limits, safeguarding the integrity of your subsequent synthesis steps. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes.

Proper storage is essential to maintain the chemical stability of this intermediate. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation or contamination. Our packaging options include standard 25 kg drums, with flexibility to accommodate custom requirements based on volume and logistical needs. Safety data sheets are available to guide safe handling practices within your laboratory or production facility.

Industrial Applications

This compound serves primarily as a vital intermediate in the pharmaceutical industry. It is specifically utilized in the synthetic pathways leading to certain antipsychotic medications. The high purity level ensures minimal side reactions during coupling steps, thereby improving overall yield and reducing purification burdens in later stages. Beyond its primary use, the chemical structure offers potential for exploration in medicinal chemistry research where benzisoxazole derivatives are required.

  • Supports efficient synthesis routes for complex pharmaceutical APIs.
  • Ensures consistent batch-to-batch reproducibility for large-scale manufacturing.
  • Compatible with various organic synthesis methodologies and reaction conditions.
  • Backed by global supply chain capabilities for timely delivery.
  • Available with full regulatory documentation for compliance auditing.

Our team of experts is dedicated to supporting clients with technical inquiries regarding the application of this intermediate. We understand the complexities of organic synthesis and strive to provide materials that facilitate smooth process development. By choosing our products, you gain access to a reliable supply chain committed to maintaining the highest standards of chemical quality and service excellence.