6-Fluorochromane-2-Carboxylic Acid
- CAS No.99199-60-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Fluorochromane-2-Carboxylic Acid (CAS 99199-60-7) designed for pharmaceutical synthesis. Ideal intermediate for Nebivolol production with ≥99% purity assurance.
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Product Overview
6-Fluorochromane-2-Carboxylic Acid is a specialized organic compound widely recognized for its critical role in medicinal chemistry and pharmaceutical manufacturing. As a key building block, this fluorinated chromane derivative serves as an essential intermediate in the synthesis of advanced cardiovascular therapeutic agents. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream chemical processes.
The introduction of a fluorine atom at the sixth position of the chromane ring significantly enhances the metabolic stability and bioavailability of the final drug molecule. This structural feature makes the acid particularly valuable for developing high-performance pharmaceutical formulations. We supply this material to global research institutions and manufacturing partners who require precise chemical specifications for complex synthesis routes.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 6-Fluorochromane-2-Carboxylic Acid |
| CAS Number | 99199-60-7 |
| Molecular Formula | C10H9FO3 |
| Molecular Weight | 196.18 g/mol |
| Purity | ≥99% |
| Appearance | White powder-like solid |
| Melting Point | 129.2-130.3°C |
| Boiling Point | 358.037°C at 760 mmHg |
| Density | 1.365 g/cm3 |
Industrial Applications
This chemical intermediate is primarily utilized in the pharmaceutical industry for the production of beta-blockers and related cardiovascular medications. Specifically, it acts as a precursor in the manufacturing process of Nebivolol hydrochloride. The high purity grade we offer ensures minimal impurity carryover, which is vital for meeting regulatory compliance in drug substance production.
Beyond standard pharmaceutical uses, this compound is also employed in organic synthesis research where fluorinated heterocycles are required. Its stable chemical structure allows for various derivatization reactions, making it a versatile tool for chemists developing new therapeutic candidates. Our team supports clients with technical data to optimize their synthesis pathways.
Quality Assurance and Storage
We maintain a robust quality management system to guarantee that every batch of 6-Fluorochromane-2-Carboxylic Acid meets the specified standards. Each shipment is accompanied by a Certificate of Analysis (COA) detailing physical and chemical properties. We recommend storing this product in a cool, dry, and well-ventilated area away from incompatible substances. Proper handling ensures the longevity and stability of the material during your production cycles.
