Intermediates

6-Fluorohexan-1-ol

  • CAS No.373-32-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Fluorohexan-1-ol (CAS 373-32-0), a versatile fluorinated alcohol intermediate for advanced organic synthesis.

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Product Technical Details

Product Overview

6-Fluorohexan-1-ol is a high-purity fluorinated aliphatic alcohol widely employed as a key building block in the pharmaceutical and agrochemical industries. With its unique combination of a terminal hydroxyl group and a distal fluorine atom, this compound offers enhanced metabolic stability and lipophilicity, making it particularly valuable in the design of complex organic molecules and active pharmaceutical ingredients (APIs). As a specialty fluorochemical intermediate, it supports the development of novel therapeutics and fine chemicals requiring precise molecular tuning.

Specifications

Molecular FormulaC6H13FO
Molecular Weight120.17 g/mol
Density0.92 g/cm³
Boiling Point158.2°C
Flash Point77.9°C
Refractive Index1.398
AppearanceColorless liquid
Assay≥99.0%
Moisture≤0.5%

Industrial Applications

6-Fluorohexan-1-ol serves primarily as an intermediate in multi-step organic syntheses. Its applications include:

  • Construction of fluorinated side chains in drug discovery programs targeting improved pharmacokinetic profiles.
  • Synthesis of specialty surfactants and functional polymers with tailored surface properties.
  • Preparation of chiral ligands and catalysts in asymmetric synthesis.
  • Use as a derivatization agent in analytical chemistry for enhancing detection sensitivity.

Stored in a cool, well-ventilated area away from ignition sources, this product is typically supplied in 225 kg drums or customized packaging to meet global regulatory and logistical requirements. As a non-controlled, non-narcotic chemical, it is fully compliant with international trade standards for B2B chemical commerce.