Intermediates

6-Fluoroindole-2-carboxylic acid

  • CAS No.3093-97-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Fluoroindole-2-carboxylic acid (CAS 3093-97-8) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.

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Product Technical Details

Product Overview

6-Fluoroindole-2-carboxylic acid is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. As a derivative of the indole scaffold, this molecule incorporates a fluorine atom at the sixth position, which significantly enhances its metabolic stability and lipophilicity when integrated into larger pharmaceutical structures. Our facility produces this compound under strict quality control standards to ensure consistency for research and industrial applications.

The introduction of fluorine into organic molecules is a strategic move in drug design, often improving bioavailability and binding affinity. This carboxylic acid derivative provides a versatile reactive site for further functionalization, making it an invaluable asset for chemists developing new therapeutic agents or advanced materials.

Key Specifications

ParameterValue
Chemical Name6-Fluoroindole-2-carboxylic acid
CAS Number3093-97-8
Molecular FormulaC9H6FNO2
Molecular Weight179.148 g/mol
AppearanceBrown powder
Assay≥98.0%
Density1.5±0.1 g/cm3
Boiling Point422.2±25.0 °C at 760 mmHg
Flash Point209.1±23.2 °C

Industrial Applications

This chemical intermediate is primarily utilized in the synthesis of complex pharmaceutical compounds. The indole nucleus is prevalent in numerous biologically active molecules, and the fluorine substitution offers distinct advantages in structure-activity relationship studies. Researchers leverage this building block to create diverse libraries of compounds for screening against various biological targets.

  • Pharmaceutical Intermediate Synthesis
  • Medicinal Chemistry Research
  • Heterocyclic Compound Construction
  • Organic Methodology Development

Beyond pharmaceuticals, this compound finds utility in the development of agrochemicals and functional materials where specific electronic properties are required. The high purity level ensures that downstream reactions proceed with minimal side products, optimizing yield and reducing purification costs.

Quality Assurance and Packaging

We understand that consistency is paramount in chemical manufacturing. Every batch of 6-Fluoroindole-2-carboxylic acid undergoes rigorous analytical testing, including HPLC and NMR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified standards.

Standard packaging consists of 25 kg drums, which are designed to protect the material from moisture and physical damage during transit. We also offer flexible packaging solutions tailored to specific customer requirements, ensuring safe delivery regardless of order size. Our logistics network supports global distribution, maintaining the integrity of the product throughout the supply chain.

Storage and Handling

To maintain optimal quality, this product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. The container must remain tightly sealed when not in use to prevent exposure to atmospheric moisture. Proper personal protective equipment, including gloves and safety goggles, should be worn during handling to ensure laboratory safety standards are met.