6-Fluoroindole
- CAS No.399-51-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
6-Fluoroindole (CAS 399-51-9) is a high-purity heterocyclic intermediate essential for advanced pharmaceutical organic synthesis and research applications.
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Product Overview
6-Fluoroindole represents a critical fluorinated heterocyclic building block extensively utilized in modern medicinal chemistry and advanced organic synthesis. As a specialized intermediate, this compound features a fluorine substitution at the sixth position of the indole ring, offering unique electronic and steric properties that enhance the biological activity and metabolic stability of downstream pharmaceutical candidates. Our facility produces this material under strict quality control protocols to ensure consistency for research and industrial applications.
Manufactured by a seasoned global chemical supplier, this product is designed to meet the rigorous demands of pharmaceutical R and D departments and process chemistry teams. The introduction of fluorine atoms into organic structures is a key strategy in drug design, and our 6-Fluoroindole serves as a reliable precursor for developing kinase inhibitors, receptor modulators, and other therapeutic agents. We prioritize supply chain reliability to support continuous manufacturing operations.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 399-51-9 |
| Chemical Name | 6-Fluoroindole |
| Molecular Formula | C8H6FN |
| Molecular Weight | 135.138 |
| Appearance | White to light yellow crystalline powder |
| Purity (Assay) | ≥98.0% |
| Melting Point | 72-76 °C |
| Boiling Point | 258.0±13.0 °C |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 109.9±19.8 °C |
Quality Assurance and Handling
We understand that reproducibility is paramount in chemical synthesis. Every batch of 6-Fluoroindole undergoes comprehensive analytical testing, including HPLC and NMR verification, to confirm structural integrity and purity levels. A Certificate of Analysis (COA) is provided with each shipment to validate compliance with specified standards. Our manufacturing process adheres to international safety and environmental regulations, ensuring a sustainable supply chain for our partners.
- Strict quality control measures for batch-to-batch consistency.
- Comprehensive documentation including COA and MSDS.
- Secure packaging to maintain stability during transit.
- Responsive technical support for synthesis optimization.
Storage and Stability
To maintain optimal chemical stability, 6-Fluoroindole should be stored in a cool, ventilated environment away from direct sunlight and moisture. The recommended storage temperature is between 2-8°C for long-term preservation. Proper sealing of containers is essential to prevent oxidation or degradation. When handled according to safety guidelines, this material exhibits excellent stability, ensuring it remains ready for use in sensitive synthetic routes. We recommend following standard laboratory safety procedures when handling this compound.
Industrial Applications
Primarily utilized as an intermediate in organic synthesis, this fluorinated indole derivative supports the production of complex pharmaceutical APIs. It is particularly valuable in the construction of heterocyclic frameworks found in oncology, neurology, and cardiovascular therapeutic areas. Researchers value this building block for its reactivity profile, which facilitates efficient coupling reactions and functional group transformations. Whether for scale-up processes or laboratory research, our supply ensures timely delivery to support your project milestones. Contact our sales team for custom packaging solutions and bulk pricing inquiries.
