Intermediates

6-Fluoronicotinic Acid

  • CAS No.403-45-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 6-Fluoronicotinic Acid (CAS 403-45-2) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical manufacturing processes.

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Product Technical Details

Product Overview

6-Fluoronicotinic Acid stands as a pivotal fluorinated heterocyclic compound within the realm of modern organic chemistry. As a specialized pyridine derivative, this chemical building block offers exceptional reactivity and stability, making it indispensable for complex molecular construction. Our manufacturing process ensures high consistency and purity, catering to the rigorous demands of research laboratories and industrial production facilities alike. The presence of the fluorine atom at the sixth position significantly enhances the metabolic stability and lipophilicity of downstream molecules, which is a critical parameter in medicinal chemistry design.

Technical Specifications

We adhere to strict quality control protocols to guarantee that every batch meets international standards. The following table outlines the key physical and chemical properties verified through our analytical laboratories.

ParameterSpecification
Chemical Name6-Fluoronicotinic Acid
CAS Number403-45-2
Molecular FormulaC6H4FNO2
Molecular Weight141.100 g/mol
AppearanceWhite to off-white solid
Assay≥98.0%
Melting Point144-148 °C
Boiling Point309.4±22.0 °C
Density1.4±0.1 g/cm3

Industrial Applications

This compound serves as a versatile intermediate in the synthesis of various high-value chemicals. In the pharmaceutical sector, it is frequently utilized in the development of kinase inhibitors and other therapeutic agents where fluorination is required to improve bioavailability. The agrochemical industry also leverages this material for creating novel pesticides and herbicides with enhanced environmental profiles. Furthermore, material scientists employ this acid derivative in the creation of advanced polymers and functional materials. Its compatibility with various coupling reactions allows for flexible integration into multi-step synthesis routes.

Quality Assurance and Logistics

Our production facilities operate under comprehensive quality management systems to ensure product integrity from synthesis to shipment. Each drum is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We understand the importance of secure packaging and timely delivery in the global supply chain. Therefore, we offer robust packaging solutions that protect the material from moisture and physical damage during transit.

Why Choose Our Supply

  • Consistent high purity levels suitable for sensitive reactions
  • Scalable production capacity for bulk industrial requirements
  • Dedicated technical support for process optimization
  • Competitive pricing structures for long-term partnerships