6-Hydroxy-2-naphthimidamide Methanesulfonate Salt

Product Overview

6-Hydroxy-2-naphthimidamide Methanesulfonate Salt is a critical pharmaceutical intermediate utilized extensively in the synthesis of advanced therapeutic agents. Identified by CAS number 82957-06-0, this compound serves as a foundational building block in the manufacturing process of protease inhibitors and anticoagulant medications. Our facility specializes in the production of this high-quality salt form, ensuring consistent molecular stability and optimal reactivity for downstream chemical transformations.

As a dedicated manufacturer in the fine chemicals sector, we understand the stringent requirements of pharmaceutical synthesis. This product is engineered to meet rigorous purity standards, facilitating efficient reaction pathways while minimizing impurity profiles in the final active pharmaceutical ingredient. The methanesulfonate salt form enhances solubility and handling characteristics, making it a preferred choice for process chemists and production managers alike.

Key Specifications

We maintain strict quality control protocols to guarantee that every batch meets the specified technical parameters. The following table outlines the standard physical and chemical properties associated with this intermediate. Custom specifications may be available upon request for specific synthetic routes.

Industrial Applications

The primary application of this chemical intermediate is in the synthesis of Nafamostat Mesylate, a potent serine protease inhibitor used clinically for anticoagulation and the treatment of pancreatitis. The high purity of our 6-Hydroxy-2-naphthimidamide Methanesulfonate Salt ensures that the subsequent coupling reactions proceed with high yield and minimal byproduct formation. This efficiency is crucial for scaling up production from laboratory pilot batches to commercial manufacturing volumes.

Beyond its direct role in Nafamostat production, this compound is valuable for research and development in medicinal chemistry. It serves as a reference standard and a key substrate for exploring novel naphthalene-based derivatives. Our technical team supports clients with documentation regarding safety data and compatibility with various solvents and reagents commonly used in organic synthesis.

Quality Assurance and Packaging

Quality is the cornerstone of our manufacturing philosophy. Each production lot undergoes comprehensive analysis using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy. A Certificate of Analysis is provided with every shipment, detailing the exact purity levels and test results. We adhere to international safety standards to ensure the product remains stable during transit.

Standard packaging consists of 25kg cardboard drums, designed to protect the contents from moisture and physical damage. For larger volume requirements, we offer flexible packaging solutions tailored to customer logistics. All containers are clearly labeled with product identification, batch numbers, and safety warnings to comply with global transportation regulations.

Storage and Handling

To maintain optimal quality, this intermediate should be stored in a cool, dry, and well-ventilated area. It is essential to keep the container tightly closed when not in use to prevent exposure to atmospheric moisture, which could affect the loss on drying specifications. Protection from strong light and heat sources is also recommended to preserve chemical integrity over extended storage periods. Proper handling procedures, including the use of personal protective equipment, should be followed during weighing and transfer operations.