Intermediates

(6-Hydroxynaphthalen-2-yl)boronic acid

  • CAS No.173194-95-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (6-Hydroxynaphthalen-2-yl)boronic acid for pharmaceutical synthesis. Reliable supply with full documentation and custom packaging options available for global partners.

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Product Technical Details

Product Overview

Welcome to our detailed product specification for (6-Hydroxynaphthalen-2-yl)boronic acid, a critical compound in modern organic synthesis. This specialized boronic acid derivative is engineered to meet the rigorous demands of pharmaceutical research and development laboratories worldwide. As a key building block, it facilitates complex molecular constructions essential for developing new therapeutic agents. Our commitment to quality ensures that every batch undergoes strict analytical testing to guarantee consistency and reliability for your synthesis projects.

Chemical Properties and Structure

The chemical structure features a naphthalene backbone substituted with a hydroxyl group and a boronic acid moiety. This unique configuration enhances its reactivity in cross-coupling reactions, particularly Suzuki-Miyaura couplings. The presence of the hydroxyl group allows for further functionalization, making it a versatile intermediate for medicinal chemists. Our manufacturing process utilizes advanced purification techniques to remove impurities that could inhibit reaction yields or complicate downstream processing. We understand that purity is paramount in drug discovery, and our protocols reflect this industry standard.

Technical Specifications

Technical specifications are verified through high-performance liquid chromatography and nuclear magnetic resonance spectroscopy. The physical appearance is typically a white powder, indicating high levels of crystallinity and purity. Moisture content is strictly controlled to prevent hydrolysis during storage. The following table outlines the key parameters guaranteed with every shipment:

ParameterSpecification
CAS Number173194-95-1
Molecular FormulaC10H9BO3
Molecular Weight187.99 g/mol
AppearanceWhite powder
Assay≥98.0%
Water Content≤0.50%
Melting Point218-224°C

Industrial Applications

In terms of industrial applications, this compound serves primarily as a pharmaceutical intermediate. It is extensively used in the synthesis of biologically active molecules where the naphthalene scaffold is required. Researchers utilize this boronic acid to introduce specific aromatic systems into larger drug candidates. The stability of the boronic acid group under various conditions makes it suitable for multi-step synthesis routes. Beyond standard pharmaceutical intermediates, this compound supports the development of targeted therapies. The naphthalene structure is often found in compounds exhibiting specific biological activities. By providing a high-purity starting material, we enable researchers to focus on innovation rather than troubleshooting raw material variability. The compatibility with various catalysts allows for flexible reaction conditions.

Quality Assurance and Storage

Proper storage and handling are essential to maintain product integrity. We recommend storing the material in a cool, dry place away from direct sunlight. Containers should remain tightly closed to prevent exposure to atmospheric moisture, which can degrade boronic acids over time. Our packaging options include standard drums as well as custom solutions tailored to specific client logistics requirements. Our quality assurance team implements a multi-stage testing regime. Raw materials are screened upon arrival, and in-process checks monitor reaction progress. Final product release requires meeting all specified criteria for assay and impurities. This diligence minimizes risk in your production scale-up. We also offer technical consultation to assist with process optimization involving this specific chemical entity. We provide comprehensive documentation including Certificates of Analysis for every lot. Partner with us for reliable supply chain solutions and technical support for your chemical synthesis needs.