6-Iodo-1H-indazole
- CAS No.261953-36-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Iodo-1H-indazole (CAS 261953-36-0) designed for pharmaceutical synthesis, specifically as a key intermediate for Axitinib production.
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Product Overview
6-Iodo-1H-indazole is a specialized heterocyclic compound widely recognized in the pharmaceutical industry for its critical role in medicinal chemistry and drug synthesis. As a halogenated indazole derivative, this chemical serves as a vital building block for constructing complex molecular architectures. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream API manufacturing.
The presence of the iodine substituent at the sixth position of the indazole ring makes this compound particularly valuable for cross-coupling reactions, such as Suzuki or Heck couplings. These reactions are fundamental in the development of kinase inhibitors and other targeted therapeutics. We specialize in supplying high-grade materials that meet the rigorous demands of modern pharmaceutical research and production.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 6-Iodo-1H-indazole |
| CAS Number | 261953-36-0 |
| Molecular Formula | C7H5IN2 |
| Molecular Weight | 244.03 g/mol |
| Appearance | Yellow crystalline powder |
| Purity | ≥98.0% |
| Density | 2.082 g/cm3 |
| Boiling Point | 358.2°C |
| Flash Point | 170.4°C |
| Refractive Index | 1.788 |
Industrial Applications
The primary application of 6-Iodo-1H-indazole is in the synthesis of Axitinib, a potent kinase inhibitor used in the treatment of advanced renal cell carcinoma. Beyond this specific API, the compound is utilized in various research projects focused on oncology and cardiovascular diseases. Its structural properties allow chemists to introduce diverse functional groups efficiently, facilitating the discovery of new drug candidates.
Our clients leverage this intermediate for scale-up production, ensuring that their manufacturing processes remain compliant with international regulatory standards. Whether for early-stage drug discovery or late-stage commercial production, our material provides the necessary chemical integrity to support successful outcomes.
Quality Assurance and Packaging
We understand that purity and consistency are paramount in pharmaceutical manufacturing. Each batch of 6-Iodo-1H-indazole undergoes comprehensive testing using advanced analytical techniques such as HPLC, NMR, and Mass Spectrometry. We provide a Certificate of Analysis (COA) with every shipment to verify compliance with specified parameters.
- Strict quality control protocols at every production stage.
- Stable supply chain ensuring timely delivery globally.
- Custom packaging solutions available upon request.
- Technical support for synthesis optimization and troubleshooting.
Standard packaging consists of 25 kg drums, designed to protect the product from moisture and light during transit. For larger volume requirements, we offer flexible packaging options tailored to customer logistics. Storage recommendations include keeping the material in a cool, ventilated place away from incompatible substances. By choosing our company as your partner, you gain access to decades of expertise in fine chemical manufacturing and a commitment to excellence that drives innovation in the pharmaceutical sector.
