6-Methoxy-5-methylpyridin-3-amine
- CAS No.867012-70-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-Methoxy-5-methylpyridin-3-amine (CAS 867012-70-2), a valuable pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
6-Methoxy-5-methylpyridin-3-amine is a high-purity, functionalized pyridine derivative widely employed as a key building block in complex organic synthesis. With its unique substitution pattern—featuring both methoxy and methyl groups adjacent to the amine functionality—it offers versatile reactivity for constructing heterocyclic scaffolds essential in modern medicinal chemistry and crop protection agent development.
Specifications
| Molecular Formula | C₇H₁₀N₂O |
|---|---|
| Molecular Weight | 138.167 g/mol |
| CAS Number | 867012-70-2 |
| Appearance | Pale purple to purple powder |
| Assay | ≥98.0% |
| Moisture | ≤0.5% |
| Density | 1.1 ± 0.1 g/cm³ |
| Boiling Point | 267.6 ± 35.0 °C at 760 mmHg |
| Flash Point | 115.6 ± 25.9 °C |
Industrial Applications
This compound serves primarily as a specialty intermediate in the synthesis of active pharmaceutical ingredients (APIs) and agrochemical actives. Its electron-rich pyridine core enables selective cross-coupling, nucleophilic substitution, and cyclization reactions, making it ideal for constructing nitrogen-containing heterocycles with tailored biological activity.
- Used in multi-step syntheses requiring regioselective functionalization of pyridine rings
- Suitable for Suzuki, Buchwald-Hartwig, and other transition-metal-catalyzed transformations
- Compatible with standard purification and handling protocols in GMP-compliant environments
Stored in a cool, well-ventilated area away from oxidizing agents, this intermediate is typically supplied in 25 kg drums or customized packaging to meet client-specific logistics and regulatory requirements.
