Intermediates

6-Methoxyquinoline

  • CAS No.5263-87-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 6-Methoxyquinoline (CAS 5263-87-6) is a vital pharmaceutical intermediate. Ideal for organic synthesis and research applications with ≥98% assay.

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Product Technical Details

Product Overview

6-Methoxyquinoline is a sophisticated heterocyclic organic compound widely recognized for its utility in advanced chemical synthesis. As a key derivative of the quinoline scaffold, this substance serves as an essential building block in the development of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures that every batch meets rigorous international standards for purity and stability, making it a reliable choice for research laboratories and industrial production facilities alike.

The presence of the methoxy group at the sixth position of the quinoline ring enhances its reactivity profile, allowing for versatile functionalization in multi-step synthesis routes. This chemical is particularly valued in medicinal chemistry for constructing bioactive molecules where the quinoline core provides structural integrity and specific pharmacological properties. We commit to delivering consistent quality to support your innovation pipeline.

Technical Specifications

Our production facility utilizes state-of-the-art distillation and purification technologies to achieve superior product quality. The physical properties of 6-Methoxyquinoline are carefully monitored to ensure compliance with specified parameters. Below is a detailed summary of the typical technical data associated with this intermediate.

ParameterSpecification
Chemical Name6-Methoxyquinoline
CAS Number5263-87-6
Molecular FormulaC10H9NO
Molecular Weight159.19 g/mol
AppearanceYellow transparent liquid
Purity (GC)≥98.0%
Density1.15 g/mL at 20 °C
Boiling Point140-146 °C at 15 mm Hg
Refractive Indexn20/D 1.625
Flash Point>230 °F

Quality Assurance and Analysis

Quality control is paramount in the production of fine chemical intermediates. Each lot of 6-Methoxyquinoline undergoes comprehensive analytical testing before release. Our standard analysis includes gas chromatography (GC) to verify assay levels, ensuring that the purity consistently exceeds 98%. Moisture content is strictly controlled to remain below 0.5%, preventing hydrolysis or degradation during storage.

In recent batch testing, results indicated an assay of 99.1%, demonstrating our capability to exceed standard requirements. The appearance is verified as a light brown-yellow oily liquid, conforming to physical expectations. We provide a Certificate of Analysis (COA) with every shipment, offering full transparency regarding test methods and results. This documentation supports regulatory compliance and quality audits for our global partners.

Storage and Handling

To maintain the integrity of 6-Methoxyquinoline, proper storage conditions are essential. The product is stable at room temperature when kept in closed containers under normal handling conditions. However, for long-term preservation, we recommend storing the material in a cool, dry environment between 2-8°C. Containers should be tightly sealed to prevent exposure to moisture and air, which could affect the refractive index or purity over extended periods.

When handling this chemical, standard safety protocols for organic liquids should be followed. Ensure adequate ventilation and use appropriate personal protective equipment. As a stable intermediate, it poses minimal risk when managed correctly, but care should be taken to avoid contact with strong oxidizing agents. Our packaging is designed to ensure safe transport across global supply chains, minimizing the risk of leakage or contamination.

Industrial Applications

The versatility of 6-Methoxyquinoline makes it suitable for a wide range of industrial applications. Primarily, it is utilized as a precursor in the synthesis of pharmaceutical APIs, where the quinoline structure is a common motif in antimalarial, anticancer, and antimicrobial agents. Additionally, it serves as a valuable reagent in the development of agrochemicals and functional materials.

  • Pharmaceutical intermediate for heterocyclic drug synthesis
  • Building block for organic research and development
  • Component in specialized agrochemical formulations
  • Reagent for material science applications

Our team supports customers with technical expertise regarding synthesis routes and integration into existing manufacturing processes. Whether you require bulk quantities for large-scale production or smaller batches for research purposes, we are equipped to meet your demands with precision and reliability.