6-(Trifluoromethyl)-1H-indole-2-carboxylic acid
- CAS No.327-20-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate designed for advanced organic synthesis and drug discovery applications with verified quality standards.
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Product Overview
6-(Trifluoromethyl)-1H-indole-2-carboxylic acid represents a sophisticated building block within the realm of modern pharmaceutical chemistry. As a specialized indole derivative, this compound is engineered to facilitate the construction of complex molecular architectures required in contemporary drug discovery pipelines. The incorporation of the trifluoromethyl group enhances metabolic stability and lipophilicity, making it a preferred choice for medicinal chemists aiming to optimize lead compounds.
Our manufacturing facility adheres to strict quality control protocols to ensure every batch meets rigorous international standards. We understand the critical nature of supply chain reliability in the pharmaceutical sector, which is why we maintain consistent inventory levels and provide comprehensive documentation for every shipment.
Key Chemical Properties
This compound exhibits distinct physicochemical characteristics that make it suitable for various synthetic transformations. The presence of the carboxylic acid functionality allows for versatile coupling reactions, while the indole core provides a robust scaffold for further functionalization. The trifluoromethyl substituent at the sixth position imparts unique electronic properties that can significantly influence the biological activity of the final active pharmaceutical ingredient.
| Parameter | Specification |
|---|---|
| CAS Number | 327-20-8 |
| Molecular Formula | C10H6F3NO2 |
| Molecular Weight | 229.155 g/mol |
| Appearance | White to light yellow crystalline powder |
| Assay | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 402.5±40.0 °C at 760 mmHg |
| Flash Point | 197.2±27.3 °C |
Industrial Applications
Primarily utilized as a key intermediate in organic synthesis, this material serves as a precursor for a wide range of bioactive molecules. It is extensively employed in the development of kinase inhibitors, receptor modulators, and other therapeutic agents targeting various disease states. The high purity level ensures minimal impurity profiles in downstream processes, reducing the need for extensive purification steps during scale-up.
- Pharmaceutical drug discovery and development
- Synthesis of heterocyclic compounds
- Creation of specialized chemical libraries
- Academic and industrial research projects
Quality Assurance and Logistics
We prioritize product integrity from synthesis to delivery. Each batch undergoes thorough analytical testing, including HPLC and NMR verification, to confirm identity and purity. A Certificate of Analysis (COA) is provided with every order, ensuring full transparency and compliance with regulatory requirements. Our packaging solutions are designed to maintain stability during transit, protecting the material from moisture and light exposure.
Storage recommendations include keeping the product in a cool, ventilated environment away from incompatible substances. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom requirements based on specific client needs. Our global logistics network ensures timely delivery to research facilities and manufacturing plants worldwide.
