6-(Trifluoromethyl)pyridin-3-ol
- CAS No.216766-12-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 6-(Trifluoromethyl)pyridin-3-ol (CAS 216766-12-0) is a premium fluorinated building block designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
6-(Trifluoromethyl)pyridin-3-ol represents a critical fluorinated heterocyclic building block extensively utilized in modern medicinal chemistry and agrochemical development. As a specialized pyridine derivative, this compound introduces a trifluoromethyl group onto the pyridine ring, significantly enhancing metabolic stability and lipophilicity in downstream molecular structures. Our manufacturing process ensures consistent quality suitable for complex organic synthesis routes requiring high precision and reliability.
The incorporation of fluorine atoms into pharmaceutical candidates is a strategic approach to improve bioavailability and binding affinity. This specific intermediate serves as a versatile precursor for various therapeutic agents, allowing chemists to construct sophisticated molecular architectures with enhanced physicochemical properties. We maintain strict control over production parameters to deliver material that meets rigorous international standards for research and industrial applications.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 6-(Trifluoromethyl)pyridin-3-ol |
| CAS Number | 216766-12-0 |
| Molecular Formula | C6H4F3NO |
| Molecular Weight | 163.10 g/mol |
| Appearance | White to light-yellow solid |
| Assay (Purity) | ≥98.0% |
| Density | 1.423 g/cm3 |
| Boiling Point | 286.7°C |
| Flash Point | 127.2°C |
Industrial Applications
This fluorinated pyridine derivative is primarily employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique structural features make it invaluable for developing novel compounds targeting various biological pathways. Additionally, it finds application in the agrochemical sector for creating advanced crop protection agents with improved environmental profiles.
- Pharmaceutical intermediate for drug discovery programs
- Building block for fluorinated heterocyclic compounds
- Agrochemical synthesis for herbicides and pesticides
- Material science applications requiring stable aromatic systems
- Custom synthesis projects requiring high-purity precursors
Quality Assurance and Handling
Quality is paramount in our production facility. Each batch of 6-(Trifluoromethyl)pyridin-3-ol undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer specifications. Our quality management system adheres to strict protocols to minimize impurities and guarantee batch-to-batch consistency.
For optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures include using appropriate personal protective equipment during transfer and processing. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements based on specific logistical needs. Our global supply chain ensures timely delivery to support continuous manufacturing operations worldwide.
