7-Methoxy-1-naphthylacetonitrile
- CAS No.138113-08-3
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 7-Methoxy-1-naphthylacetonitrile (CAS 138113-08-3) designed for pharmaceutical synthesis. Ideal intermediate for Agomelatine production with β₯99% assay.
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Product Overview
7-Methoxy-1-naphthylacetonitrile is a specialized organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical agents. As a key building block, this naphthyl derivative offers exceptional stability and reactivity, making it indispensable for complex multi-step organic transformations. Our manufacturing process ensures consistent quality, catering to the rigorous demands of the global pharmaceutical industry. This compound is particularly valued for its high purity profile, which minimizes downstream purification challenges during API production.
The chemical structure features a methoxy-substituted naphthalene ring linked to an acetonitrile group. This specific configuration provides unique electronic properties that facilitate selective reactions in medicinal chemistry. Researchers and process chemists rely on this intermediate for its predictable behavior in nucleophilic substitutions and cyclization reactions. By sourcing from a dedicated manufacturer, clients secure a stable supply chain essential for continuous production schedules.
Technical Specifications
We adhere to strict quality control protocols to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical parameters verified through our analytical laboratories. Each certificate of analysis (COA) accompanies the shipment to ensure full traceability and compliance.
| Parameter | Specification |
|---|---|
| CAS Number | 138113-08-3 |
| Molecular Formula | C13H11NO |
| Molecular Weight | 197.23 g/mol |
| Appearance | White powder |
| Purity (HPLC) | ≥99.0% |
| Water Content | <0.2% |
| Sulfated Ash | <0.5% |
| Melting Point | 81-83°C |
| Boiling Point | 374.3°C at 760 mmHg |
Industrial Applications
The primary application of 7-Methoxy-1-naphthylacetonitrile lies in the pharmaceutical sector, specifically serving as a vital intermediate in the synthesis of Agomelatine. Agomelatine is a therapeutic agent used in the management of depressive disorders, acting as a melatonin receptor agonist. The precision required in producing such therapeutics demands starting materials with impeccable purity levels to avoid impurity carryover. Our product is optimized to support these high-stakes synthesis routes.
Beyond this specific application, the compound serves as a versatile precursor in organic synthesis laboratories. It is utilized in the development of novel chemical entities where the naphthylacetonitrile scaffold is required. The robustness of the methoxy group allows for further functionalization, enabling chemists to explore diverse chemical spaces during drug discovery phases. This versatility makes it a valuable asset for both large-scale manufacturing and research-scale experimentation.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Every production batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and other advanced analytical techniques. We maintain comprehensive documentation for each lot, ensuring full compliance with international regulatory expectations. Our facility operates under strict environmental controls to prevent contamination and ensure product integrity from synthesis to packaging.
Proper storage is essential to maintain the chemical stability of 7-Methoxy-1-naphthylacetonitrile. The product should be kept in tightly closed containers to protect against moisture and atmospheric oxidation. We recommend storing the material in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Under these conditions, the shelf life is significantly extended, ensuring that the material remains within specification until use. We offer flexible packaging options, including 25kg cardboard drums, to suit various logistical requirements.
