Intermediates

8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline

  • CAS No.100331-89-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Indacaterol. Available in bulk quantities with full COA support.

Request Bulk Pricing

Product Technical Details

Product Overview

8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline is a specialized organic compound designed for use in advanced pharmaceutical synthesis. As a critical building block, this intermediate plays a pivotal role in the production chain of complex therapeutic agents. Our facility ensures that every batch meets rigorous quality standards, providing reliability for downstream manufacturing processes.

This quinoline derivative is characterized by its specific structural configuration, which facilitates efficient coupling reactions in multi-step synthesis pathways. The presence of the benzyloxy and bromoacetyl functional groups allows for versatile chemical modifications, making it an essential component for research and development teams focused on respiratory therapeutics and related pharmacological categories.

Technical Specifications

We maintain strict control over the physical and chemical properties of this material to ensure consistency across all production lots. The following table outlines the key parameters verified through our quality assurance protocols:

ParameterSpecification
CAS Number100331-89-3
Molecular FormulaC18H14BrNO3
Molecular Weight372.213 g/mol
AppearanceOff-white powder
Assay (Purity)≥98.0%
Density1.5±0.1 g/cm3
Boiling Point596.4±45.0 °C at 760 mmHg
Flash Point314.5±28.7 °C

Quality Assurance and Testing

Quality is the cornerstone of our manufacturing process. Each batch of 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. These methods confirm the structural integrity and purity levels required for pharmaceutical applications.

We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for identity, assay, and impurities. Our commitment to transparency ensures that our partners have full visibility into the quality of the materials they integrate into their supply chains.

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of Indacaterol, a long-acting beta-agonist used in the management of chronic obstructive pulmonary disease (COPD). The high purity of our product supports efficient reaction yields and minimizes the formation of unwanted byproducts during the manufacturing of the final active pharmaceutical ingredient (API).

Beyond its primary application, this quinoline derivative serves as a valuable tool in organic synthesis research, enabling chemists to explore new reaction pathways and develop novel molecular structures within the heterocyclic compound family.

Packaging and Storage

To preserve the stability and integrity of the product, we offer standardized packaging solutions tailored to industrial needs. The standard package size is 25 kg per drum, though we accommodate custom packaging requirements based on specific client logistics and volume needs.

Storage recommendations include keeping the material in a cool, well-ventilated area away from direct sunlight and moisture. Proper handling procedures should be followed to maintain the chemical properties over extended storage periods. Our logistics team ensures secure global shipping with compliance to all relevant hazardous material regulations.

Why Choose Our Supply

As a global manufacturer with decades of experience in fine chemicals, we offer competitive bulk pricing without compromising on quality. Our supply chain is optimized for reliability, ensuring timely delivery to support your production schedules. We are dedicated to fostering long-term partnerships through consistent product performance and responsive customer support.