(2S)-Amino(3-hydroxyadamantan-1-yl)acetic acid

Product Overview

(2S)-Amino(3-hydroxyadamantan-1-yl)acetic acid is a specialized pharmaceutical intermediate characterized by its unique adamantane scaffold and chiral amino acid structure. This compound plays a pivotal role in the synthetic pathway of Saxagliptin, a prominent dipeptidyl peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes. Our manufacturing process ensures strict stereochemical control, delivering the (2S) enantiomer with exceptional optical purity required for downstream API production.

As a key building block, this molecule combines the rigidity of the tricyclic adamantane system with the functional versatility of an alpha-amino acid. This combination enhances the binding affinity and metabolic stability of the final therapeutic agent. We supply this material to global pharmaceutical partners who demand consistent quality and regulatory compliance for their drug development pipelines.

Technical Specifications

Industrial Applications

The primary application of this compound is in the synthesis of Saxagliptin and its hydrochloride salt. It acts as a crucial chiral precursor that defines the pharmacological activity of the final drug substance. Beyond diabetes treatment, adamantane derivatives are increasingly explored in various neurological and antiviral research contexts due to their ability to cross biological barriers effectively.

• Essential intermediate for DPP-4 inhibitor manufacturing
• Used in the production of Saxagliptin hydrochloride
• Supports custom synthesis for novel adamantane-based therapeutics
• Compatible with standard peptide coupling and protection strategies

Quality Assurance and Handling

We adhere to rigorous quality control standards to ensure every batch meets the specified purity and stereochemical requirements. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against international pharmacopoeia methods. Proper handling is essential to maintain product integrity during storage and transport.

Storage should be in a cool, dry, and well-ventilated area, protected from moisture and strong light. Containers must remain tightly closed when not in use to prevent degradation. We offer flexible packaging options, including 25kg cardboard drums, tailored to meet specific logistical needs of our international clientele.