Intermediates

Azetidin-3-one Hydrochloride

  • CAS No.17557-84-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Azetidin-3-one Hydrochloride is a high-purity pharmaceutical intermediate used in advanced organic synthesis. We supply ≥98% assay off-white powder with global logistics support.

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Product Technical Details

Product Overview

Azetidin-3-one Hydrochloride represents a critical heterocyclic building block within the realm of modern medicinal chemistry and organic synthesis. As a stabilized hydrochloride salt of the corresponding ketone, this compound offers enhanced handling properties and shelf stability compared to its free base form. Our facility specializes in the production of this key intermediate, ensuring that every batch meets rigorous international standards for purity and consistency. This chemical is primarily utilized by research laboratories and pharmaceutical manufacturing units engaged in the development of complex therapeutic agents.

The molecular structure features a four-membered azetidine ring with a ketone functionality at the third position, protonated to form the hydrochloride salt. This specific configuration makes it an invaluable precursor for constructing more elaborate nitrogen-containing heterocycles. Our commitment to quality ensures that researchers and process chemists can rely on our material for reproducible results in multi-step synthesis pathways.

Technical Specifications

ParameterSpecification
Chemical NameAzetidin-3-one Hydrochloride
CAS Number17557-84-5
Molecular FormulaC3H6ClNO
Molecular Weight107.539 g/mol
AppearanceOff-white powder
Assay (Purity)≥98.0%
Boiling Point139.7ºC at 760 mmHg
Flash Point76.8ºC

Industrial Applications

This compound serves as a versatile intermediate in the synthesis of various pharmaceutical active ingredients. Its primary application lies in the construction of beta-lactam analogues and other constrained ring systems that are essential for biological activity in numerous drug classes. Process chemists utilize Azetidin-3-one Hydrochloride to introduce specific nitrogenous motifs into larger molecular frameworks. The high purity level of our product minimizes the formation of side products during downstream reactions, thereby improving overall yield and reducing purification costs.

Beyond pharmaceuticals, this building block finds utility in agrochemical research and material science where specialized heterocyclic structures are required. The hydrochloride salt form facilitates solubility in polar solvents, making it compatible with a wide range of reaction conditions. Whether used in scale-up processes or early-stage drug discovery, our material provides a reliable foundation for chemical innovation.

Quality Assurance and Packaging

Quality control is paramount in our manufacturing process. Each production lot undergoes comprehensive analysis using advanced chromatographic and spectroscopic methods to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for that batch. Our facilities adhere to strict safety and environmental protocols to ensure sustainable production practices.

  • Packaged in 25 kg drums for optimal protection during transit.
  • Custom packaging solutions available upon client request.
  • Stored in cool, ventilated areas to maintain stability.
  • Global shipping capabilities with secure logistics partners.

We understand the importance of supply chain reliability for our B2B partners. Our inventory management systems are designed to fulfill bulk orders promptly while maintaining the integrity of the chemical product. For specific technical inquiries or custom synthesis requirements, our expert team is available to provide detailed support and documentation.