Intermediates

Benzo[d]isothiazol-3-one

  • CAS No.2634-33-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Benzo[d]isothiazol-3-one (CAS 2634-33-5) designed for advanced pharmaceutical synthesis. Reliable supply for global API manufacturing projects.

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Product Technical Details

Product Overview

Benzo[d]isothiazol-3-one is a highly versatile heterocyclic organic compound that serves as a critical building block in the synthesis of complex pharmaceutical agents. Known chemically as 1,2-Benzisothiazol-3(2H)-one, this substance is characterized by its stable molecular structure and high reactivity under controlled conditions. Our facility specializes in the large-scale production of this intermediate, ensuring consistent quality for downstream manufacturing processes. The compound is extensively utilized in the development of advanced neurological therapeutics and other specialized medicinal chemistry applications.

We understand the stringent requirements of the global pharmaceutical supply chain. Therefore, every batch of Benzo[d]isothiazol-3-one undergoes rigorous quality control protocols to meet international standards. Our manufacturing process is optimized for yield and purity, making it an ideal choice for research institutions and commercial API producers seeking reliable raw materials.

Technical Specifications

The physical and chemical properties of this intermediate are critical for its performance in synthesis reactions. We maintain tight control over parameters such as melting point, density, and purity levels to ensure reproducibility in your production lines. The following table outlines the standard specifications for our commercial grade material:

ParameterSpecification
CAS Number2634-33-5
Molecular FormulaC7H5NOS
Molecular Weight151.19 g/mol
AppearanceWhite to Light Yellow Hydrated Powder
Purity (HPLC)≥98.0%
Melting Point154-158°C
Water Content≤0.15%
Chloride Content≤0.6%
Density1.367 g/cm3
Boiling Point204.5°C at 760 mmHg

Quality Assurance and Testing

Quality is the cornerstone of our operation. Each production lot is subjected to comprehensive analytical testing using high-performance liquid chromatography (HPLC) and other advanced spectroscopic methods. We verify identity, assay, and impurity profiles against strict internal benchmarks. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for that batch. This transparency allows our partners to validate materials quickly upon receipt, minimizing downtime in their manufacturing schedules.

Industrial Applications

This compound functions primarily as a key intermediate in the multi-step synthesis of various pharmaceutical active ingredients. It is particularly valued in the production of specific antipsychotic medications and related neurological therapeutics. The chemical stability of the benzisothiazole ring system makes it suitable for diverse reaction conditions, including coupling and substitution reactions. Beyond pharmaceuticals, it may also serve as a precursor in the development of specialized agrochemicals and fine chemicals where heterocyclic structures are required.

Storage and Handling

To maintain optimal stability, Benzo[d]isothiazol-3-one should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to prevent exposure to moisture and strong light, which could degrade the material over time. We recommend keeping the product away from heat sources and incompatible substances. Proper personal protective equipment (PPE) should be worn during handling to ensure safety in accordance with standard laboratory and industrial hygiene practices.

Packaging and Logistics

We offer flexible packaging solutions to accommodate various order volumes. Standard packaging includes 25kg cardboard drums, which are designed for safe international transport. Custom packaging configurations are available upon request to meet specific logistical requirements. Our logistics team ensures timely delivery with full documentation, supporting seamless integration into your supply chain. Contact our sales team today to discuss bulk pricing and availability for your upcoming projects.