Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine
- CAS No.102691-36-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine is a critical phosphoramidite reagent designed for pharmaceutical intermediate synthesis, specifically for antibiotic production.
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Product Overview
Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine, identified by CAS number 102691-36-1, represents a high-performance phosphoramidite reagent essential for modern pharmaceutical synthesis. This specialized chemical intermediate is engineered to meet the rigorous demands of organic synthesis, particularly within the production of advanced antibiotic compounds such as Ceftibuten dihydrate. Our manufacturing process ensures exceptional consistency and reliability, making it a preferred choice for research laboratories and industrial production facilities worldwide.
As a key building block in medicinal chemistry, this compound facilitates efficient phosphitylation reactions. The molecular structure, characterized by the formula C15H32N3OP, provides optimal reactivity while maintaining stability under controlled conditions. We prioritize quality assurance at every stage of production, ensuring that each batch meets or exceeds international standards for pharmaceutical intermediates.
Technical Specifications
Our commitment to quality is reflected in the precise physical and chemical properties of this product. The following table outlines the critical specifications guaranteed for every shipment:
| Parameter | Specification |
|---|---|
| CAS Number | 102691-36-1 |
| Molecular Formula | C15H32N3OP |
| Molecular Weight | 301.41 g/mol |
| Appearance | Transparent light yellow oily liquid |
| Purity | ≥98.0% |
| Density | 0.949 g/mL at 25 °C |
| Boiling Point | 100 °C at 0.5 mm Hg |
| Refractive Index | 1.470 |
| Flash Point | 177.9 ± 28.4 °C |
Applications and Usage
This phosphine derivative serves as a vital intermediate in the synthesis of cephalosporin antibiotics. Its primary application lies in the manufacturing process of Ceftibuten dihydrate, where it acts as a crucial coupling agent. The high purity level ensures minimal side reactions, leading to improved yields and reduced downstream purification costs.
- Pharmaceutical intermediate synthesis for beta-lactam antibiotics
- Organic phosphitylation reactions in fine chemical production
- Research and development for novel therapeutic agents
- Scale-up production requiring consistent reagent quality
Storage and Handling
To maintain the integrity and efficacy of Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine, proper storage protocols must be followed. The compound should be stored at temperatures between 2-8 °C in a tightly closed container. It is imperative to keep the material in a cool, dry, and well-ventilated area away from incompatible substances. Protection under common inert gas is recommended to prevent oxidation and moisture absorption, which could degrade the reagent quality. Safety data sheets and certificates of analysis are provided with every order to ensure compliant handling and usage in your facility.
