Intermediates

Boc-D-prolinol

  • CAS No.83435-58-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Boc-D-prolinol (CAS 83435-58-9) designed for pharmaceutical synthesis and chiral catalysis, available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

Boc-D-prolinol represents a highly specialized chiral building block essential for modern organic synthesis and pharmaceutical development. As a protected amino alcohol derivative, this compound serves as a critical intermediate in the construction of complex molecular architectures. Our facility produces this material under strict quality control protocols to ensure consistent stereochemical integrity and chemical purity suitable for demanding research and industrial applications.

The compound features a tert-butoxycarbonyl protecting group on the nitrogen atom of the proline ring, which provides stability during various synthetic transformations while allowing for selective deprotection when required. This specific configuration makes it an invaluable tool for chemists working on asymmetric synthesis, peptide modification, and the development of novel therapeutic agents.

Technical Specifications

We adhere to rigorous analytical standards to guarantee the performance of every batch. The following table outlines the key physical and chemical parameters verified during our quality assurance process.

ParameterSpecification
CAS Number83435-58-9
Molecular FormulaC10H19NO3
Molecular Weight201.26 g/mol
AppearanceWhite Crystalline Powder
Purity (HPLC)≥ 99.0%
Loss on Drying≤ 0.2%
Residue on Ignition≤ 0.1%
Melting Point59-62 °C
Storage Temperature0 °C

Industrial Applications

The versatility of Boc-D-prolinol extends across multiple sectors within the fine chemical and pharmaceutical industries. Its primary utility lies in its role as a chiral pool synthon, enabling the introduction of specific stereochemistry into target molecules.

  • Pharmaceutical Intermediate: Used extensively in the synthesis of active pharmaceutical ingredients (APIs) requiring chiral pyrrolidine motifs.
  • Asymmetric Catalysis: Serves as a ligand or precursor for chiral catalysts in organic transformations.
  • Peptide Chemistry: Employed in the modification of peptide chains to enhance stability or biological activity.
  • Agrochemical Development: Utilized in the creation of specialized agrochemical compounds requiring high optical purity.

Quality Assurance And Storage

Our manufacturing process emphasizes reproducibility and safety. Each production lot undergoes comprehensive testing using advanced chromatographic and spectroscopic methods. We provide a Certificate of Analysis (COA) with every shipment to verify compliance with stated specifications.

To maintain optimal stability, the product should be stored in a tightly closed container at approximately 0 °C. It is crucial to keep the material in a cool, dry environment away from direct sunlight and moisture. Proper handling ensures that the chemical properties remain intact over extended periods, supporting long-term project requirements.

We offer flexible packaging options, including standard 25 kg drums, to accommodate both laboratory-scale research and large-scale industrial production needs. Our global logistics network ensures timely delivery while maintaining the required cold chain conditions.