Boc-D-Tic-OH
- CAS No.11592-35-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Boc-D-Tic-OH (CAS 11592-35-1), a valuable chiral building block for pharmaceutical intermediates and complex organic synthesis.
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Product Overview
Boc-D-Tic-OH (N-tert-Butoxycarbonyl-D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) is a high-purity, non-natural amino acid derivative widely employed as a chiral intermediate in the synthesis of bioactive molecules and advanced pharmaceutical compounds. With a molecular formula of C15H19NO4 and a molecular weight of 277.32 g/mol, this compound features a rigid tetrahydroisoquinoline scaffold protected by a Boc group, offering excellent stability and stereoselectivity in multi-step syntheses.
Specifications
| Molecular Formula | C15H19NO4 |
|---|---|
| Molecular Weight | 277.32 g/mol |
| CAS Number | 11592-35-1 |
| Appearance | White or Off-white Powder |
| Purity (HPLC) | ≥98% |
| Moisture Content | <0.5% |
| Total Impurities | <0.5% |
| Melting Point | 125–126°C |
| Density | 1.2 ± 0.1 g/cm³ |
Industrial Applications
Boc-D-Tic-OH serves primarily as a specialized intermediate in the development and large-scale manufacturing of complex pharmaceutical APIs, particularly those targeting neurological and cardiovascular therapeutic areas. Its constrained conformation and defined stereochemistry make it ideal for:
- Peptidomimetic drug design and synthesis
- Chiral auxiliary applications in asymmetric synthesis
- Construction of protease inhibitors and receptor modulators
- Advanced organic synthesis requiring enantiomerically pure scaffolds
As a non-controlled, non-hazardous fine chemical, it complies with international regulatory standards for research and commercial pharmaceutical production.
Handling and Storage
Store Boc-D-Tic-OH at 2–8°C in a tightly sealed container under dry, inert conditions. Protect from light, moisture, and prolonged exposure to ambient temperature to maintain integrity and purity. Standard industrial hygiene practices are recommended during handling.
